Surgical excision of axillary lymph node(s) is standard practice in the management of invasive breast cancer. Whether sentinel or axillary lymph node excisions are performed, typically the histopathological distinction of metastatic carcinoma is straightforward. However, there are rare, though, important pathological entities that may pose a diagnostic challenge in the evaluation of axillary se...

Background. Being predictive of the entire nodal bed, sentinel lymph node biopsy (SLNB) is invaluable in the surgical management of melanoma. Although the concept is simple, sentinel lymph node (SLN) identification and removal can be technically challenging. Methods. A total of 102 consecutive patients have undergone SLNB in the Division of Plastic and Reconstructive Surgery of Soroka Universit...

Vulvar cancer is a rare gynecological malignancy with mainly lymphatic spread. Sentinel node mapping plays an important role in the management of this gynecological malignancy. In the current study, we reported our experience in sentinel node mapping of vulvar cancer and review the literature accordingly. Since the introduction of sentinel node mapping to the surgical oncology community of our ...

we report a young male with an initial excisional biopsy report of melanoma of the lower back, referred to our hospital for complete excision and sentinel lymph node (sln) biopsy.  four peritumoral intradermal tc-99m phytate injection was performed and slns were detected in both axillary and right inguinal regions. on the biopsy only the right axillary sln was metastatic leading to right axilla...

sentinel lymph node is the first regional lymph node that drains the lymph from the primary tumor. it is potentially the first nodeto receive the seeding of lymph‑borne metastatic cells. this study aimed to discuss lymphoscintigraphy procedural guidelines fordetection of sentinel node using tc‑phytate in isfahan, iran. moreover, the preliminary results of the first year’s clinical experience of...

Anorectal melanoma (AM) is a rare disease and few guidelines have been established regarding its therapeutic management. Wide local excision, or less frequently, abdominoperineal resection is the treatment of choice. We present a female patient with an excised AM who was submitted to our Nuclear Medicine department for sentinel lymph node (SLN) mapping of the area. Under rigid proctoscopy the a...

background uterine cancer stays the most prevalent gynecologic malignancy in developed countries. providing suitable solutions to treat this disease is required to the early diagnosis of this cancer. objectives the aim of this study was to evaluate the effectiveness of multiple-site lymph node sampling in patients with the endometrioid type of endometrial cancer. patients and methods demographi...

PURPOSE The aim of this study was to characterize the primary gp100(209-2M)-specific T-cell response in vaccine-draining, metastases-free lymph nodes and peripheral blood of peptide-vaccinated stage I to III melanoma patients. EXPERIMENTAL DESIGN After two or three gp100(209-2M) vaccinations, sentinel lymph nodes that drained both the primary tumor and adjacent vaccine sites were excised conc...

We present a patient with malignant melanoma on his heel. Wide local excision was performed, along with sentinel lymph node biopsy of the inguinal and popliteal lesions. The primary site was clear of tumor at all margins; the inguinal nodes were negative, but the popliteal node was positive for metastatic melanoma. Only radical popliteal lymph node dissection was performed. The patient went on ...

We report a young male with an initial excisional biopsy report of melanoma of the lower back, referred to our hospital for complete excision and sentinel lymph node (SLN) biopsy.  Four peritumoral intradermal Tc-99m phytate injection was performed and SLNs were detected in both axillary and right inguinal regions. On the biopsy only the right axillary SLN was metastatic leading to right axilla...