BACKGROUND Serum creatinine concentration is widely used as an index of renal function, but this concentration is affected by factors other than glomerular filtration rate (GFR). OBJECTIVE To develop an equation to predict GFR from serum creatinine concentration and other factors. DESIGN Cross-sectional study of GFR, creatinine clearance, serum creatinine concentration, and demographic and ...

In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...

In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...

In renal clinical trials, both slope-based and time-to-event renal outcomes have been used. These outcomes are typically based on estimates of GFR obtained using creatinine or iothalamate GFR (iGFR). The African American Study of Kidney Disease and Hypertension (AASK) was a trial in 1094 African Americans with hypertensive nephrosclerosis, which examined the effects of two levels of BP control ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: definitions of chronic kidney disease (ckd) in many catheterization laboratories have relied on the serum creatinine (scr) rather than glomerular filtration rate (gfr). regarding that ckd is the primary predisposing factor for contrast induced nephropathy (cin), we compared the sensitivity of calculated gfr by ...

Background: Glomerular filtration rate (GFR) estimation in older adults using a creatinine clearance/24-hour (CrCl) or an equation based on serum creatinine, are often considered equivalent by clinicians.

BACKGROUND Available data indicate that serum phosphate increases only when glomerular filtration rate (GFR) falls into the low range (<60 mL/min x 1.73 m(2)). GFR and serum phosphate decrease with ageing. This population-based study investigated by age-controlled analyses the relationship of GFR with serum phosphate in adults with GFR above the low range. METHODS Data were collected on age, ...

background: the presence of hyperuricemia and renal function impairment, especially in the absence of urate stone formation is strongly suggestive of lead nephropathy. the evaluation of this association is essential in areas where lead exposure is still prevalent and uncontrolled. objective: to determine the relationship between serum uric acid and renal function indices in lead-exposed workers...