Escherichia coli and yeast DNA-dependent RNA polymerases are shown to mediate efficient nascent transcript stem loop formation-dependent RNA-DNA hybrid realignment. The realignment was discovered on the heteropolymeric sequence T5C5 and yields transcripts lacking a C residue within a corresponding U5C4. The sequence studied is derived from a Roseiflexus insertion sequence (IS) element where the...

Adhesion level for the proper running of rail wheelset on track has remained a significant problem for researchers in detecting slippage to avoid accidents. In this paper, the slippage of rail wheels has been observed applying forward and lateral motions to slip velocity and torsion motion. The longitudinal and lateral forces behavior is watched with respect to traction force to note correlatio...

PURPOSE Pouch dilatation and band slippage are the most common long-term complications after laparoscopic adjustable gastric banding (LAGB). The aim of the study is to present our experience of diagnosis and management of these complications. MATERIALS AND METHODS The pars flaccida technique with anterior fixation of the fundus was routinely used. All band adjustments were performed under flu...

Evodiamine (Evo) is an indole quinazoline alkaloid isolated from the fruit of Evodia rutaecarpa Bentham. Previous studies have shown that Evo exhibits anti-proliferative anti-tumor activities in several cancer types, but its target(s) and underlying mechanism(s) of action remain unclear. In the present study, we sought to establish a cell synchron...

Future planetary rovers are expected to probe across steep sandy slopes such as crater rims where wheel slippage can be a critical problem. One possible solution is to equip locomotion mechanisms with redundant actuators so that the rovers are able to actively reconfigure themselves to adapt to the target terrain. This study modeled a reconfigurable rover to analyze the effects of reconfigurati...

Microtubule-targeting cancer drugs such as paclitaxel block cell-cycle progression at mitosis by prolonged activation of the mitotic checkpoint. Cells can spontaneously escape mitotic arrest and enter interphase without chromosome segregation by a process termed mitotic slippage that involves the degradation of cyclin B1 without mitotic checkpoint inactivation. Inducing mitotic slippage with ch...

In this report, we present a novel feature detection technique for unstructured point clouds. We introduce a generalized concept of geometric features that detects locally uniquely identifiable keypoints as centroids of area with locally minimal slippage. We extend the concept to multiple scales and extract features using multi-scale mean shift clustering. In order to validate matches between f...

INTRODUCTION There are potential effects of vibration on aircrew performance and safety when using helmet-mounted equipment. The objective of this study was to quantify the effects of head orientation and helmet center-of-gravity (CG) on head and helmet biodynamics and tracking performance during exposures to aircraft buffeting and quasi-random vibration. METHODS Three head orientations, incl...