A proteomic analysis was performed comparing normal rat soleus muscle to denervated soleus muscle at 0.5, 1, 2, 4, 6, 8 and 10 days post denervation. Muscle mass measurements demonstrated that the times of major mass changes occurred between 2 and 4 days post denervation. Proteomic analysis of the denervated soleus muscle during the atrophy process demonstrated statistically significant (at the...

Lipoprotein lipase (LPL) is a key enzyme for fatty acid and lipoprotein metabolism in muscle. However, the effect of aging on LPL regulation in skeletal muscle is unknown. We report the effect of aging on LPL regulation in the soleus (red oxidative postural) muscle and the tibialis anterior (white glycolytic non-weight-bearing) muscle in 4- and 24-mo-old Fischer 344 rats and 18- and 31-mo-old F...

The effect of insulin resistance (IR) on the adaptation of skeletal muscle loading is not well understood. Here we examine whether the soleus muscles of the lean Zucker (LZ) and insulin-resistant obese Zucker (OZ) rat exhibit differences in their ability to undergo muscle hypertrophy following 8 wk of mechanical overload. Four-week-old male LZ (n = 5) and OZ (n = 5) rats underwent unilateral su...

The influence of work-induced hypertrophy on the myosin of skeletal muscle was studied. Unilateral tenotomy of the gastrocnemius muscle (single tenotomy procedure) in normal rats led to rapid compensatory growth of the synergistic plantaris and soleus muscles. Total myosin increased with hypertrophy. The myosin from these hypertrophied muscles, however, was enzymatically and structurally identi...

The two heads of the gastrocnemius muscle, as well plantaris and soleus muscles, forms superficial muscular group in posterior compartment leg. incidental occurrence accessory slip lateral head muscle right lower limb, innervated by a twig from common peroneal nerve, is described this report. We identified an anomalous 8 cm long popliteal fossa during standard academic dissection male corpse at...

BACKGROUND Extended Soft tissue defect of leg including middle and distal parts always has been a challenge for many plastic surgeons and also a frustrated problem for patients and families. To introduce the use of the soleus muscle and reverse sural flaps as synchronous surgical treatment alternative of the leg bone exposure with large soft tissue defect, this study was conducted. METHODS T...

[Purpose] This study aimed to determine whether muscle atrophy induced by ischemic reperfusion injury in rats can be prevented by the administration of antioxidants and exercise. [Subjects] Rats were randomly divided into five groups: non-treated, ischemic, exercise, ascorbic acid and exercise, and tocopherol and exercise. [Methods] The relative weight ratio of the soleus muscle and the length ...

The orientation of muscle fibers influences the physiological cross-sectional area, the relationship between fiber shortening and aponeurosis shear, and the total force produced by the muscle. Such architectural parameters are challenging to determine particularly in vivo in multicompartment structures such as the human soleus with a complex arrangement of muscle fibers. The objective of this s...

We have previously shown that hypothermia leads to an increase in the synaptic modulating effects of ATP but not adenosine several different animal skeletal muscles. In this paper, we studied effect on amplitude–time parameters single and tetanic contractions rats’ isolated fast (1) slow (2) muscles at temperatures. found when were stimulated by electrical field (0.1 Hz, 0.5 ms, 10 V), with a d...