Spatially-offset Raman spectroscopy (SORS) is gaining an increasing popularity in detection of analytes through barriers. SORS can be applied a number different excitation modes and head-to-head comparison are limited the literature. In this study, custom system that capable switching between two spatially offset modes, namely inverse (iSORS, ring) diffuse (dSORS, enlarged flat-top circle), wer...

Spatially offset Raman spectroscopy (SORS) is a non-invasive analytical technique that allows the analysis of samples through container. This makes it an effective tool for studying food and beverage products, as can measure sample without being affected by packaging or In this study, portable SORS equipment was used first time to analyse alcoholic fermentation process white wine. Different mea...

Clinical diagnoses of bone health and fracture risk typically rely on measurements of bone density or structure, but the strength of a bone is also dependent on its chemical composition. Raman spectroscopy has been used extensively in ex vivo studies to measure the chemical composition of bone. Recently, spatially offset Raman spectroscopy (SORS) has been utilized to measure bone transcutaneous...

Time-resolved and spatially offset Raman spectroscopies have previously been demonstrated for depth analysis through strongly scattering, non-transparent materials. In this study, several series of tissue phantoms were created with varied compositions and thicknesses to compare the potential of these different Raman techniques for biomedical applications. Polydimethylsiloxane (PDMS) phantoms we...

The risk of local recurrence for breast cancers is strongly correlated with the presence of a tumor within 1 to 2 mm of the surgical margin on the excised specimen. Previous experimental and theoretical results suggest that spatially offset Raman spectroscopy (SORS) holds much promise for intraoperative margin analysis. Based on simulation predictions for signal-to-noise ratio differences among...

Solid-state batteries represent a promising technology in the field of high-energy-density and safe storage systems. Improving understanding how defects form within these cells would greatly facilitate future development, which be best served by applying nondestructive analytical tools capable characterization key components their changes during cycling and/or aging. Spatially offset Raman spec...

Non-destructive subsurface detection of encapsulated, coated, or seal-packaged foods and pharmaceuticals can help prevent distribution and consumption of counterfeit or hazardous products. This study used a Spatially Offset Raman Spectroscopy (SORS) method to detect and identify urea, ibuprofen, and acetaminophen powders contained within one or more (up to eight) layers of gelatin capsules to d...

The authenticity of olive oil has been a significant long-term challenge. Extra virgin (EVOO) is the most desirable these products and commands high price, thus unscrupulous individuals often alter its quality by adulteration with lower grade oil. Most analytical methods employed for detection food require sample collection transportation to central laboratory analysis. We explore use portable ...

Superoxide reductase (SOR), which is commonly found in prokaryotic organisms, affords protection from oxidative stress by reducing the superoxide anion to hydrogen peroxide. The reaction is catalyzed at the iron centre, which is highly conserved among the prokaryotic SORs structurally characterized to date. Reported here is the first structure of an SOR from a eukaryotic organism, the protozoan...