Current study includes an investigation of the effects Dexamethasone (Dex) drug on neural tube development. A total 60 pregnant mice were allocated into four groups at random, with 15 each group, While control group received injections a Normal Saline 0.9 %, group's members given specified dose and different times. All animals their doses through tail intravenous injection specific periods preg...

We describe the management of a 23-yr-old woman with extreme needle and mask phobia, presenting for an emergency Caesarean section for fetal distress. She also suffered from spina bifida cystica with no sensation from mid thigh. Regional anaesthesia, rapid sequence induction, and gaseous induction were not possible. She was managed successfully with i.m. ketamine followed by a more conventional...

neural tube defects (ntd) are one of the most important malformations of newborns. the aim of this research is to determine the rates of ntd, anencephaly and spina bifida cystica and the relations of these abnormalities to the factors including sex, race, ethnicity, maternal age and familial marriage in the south-east of the caspian sea border. a three-year descriptive-analytic and cross-sectio...

The operative specimens from 160 cases of spina bifida cystica were examined in detail. In seven cases the sac contained nervous tissue visible to the naked eye, the removal of which produced no clinical disability. The form taken by this non-functioning, heterotopic nervous tissue is described.

This paper discusses (1) the mortality in 295 patients with myelomeningocele born 1961-9, (2) the "quality of life" of 88 surviving patients born 1961-5, and (3) their implications for selection for treatment in spina bifida cystica. Evidence is presented that high neurological levels, the presence of severe hydrocephalus, especially if present at birth, meningitis and ventriculitis, and gross ...

OBJECTIVE To compare outcomes of fetoscopic spina bifida aperta repair (FSBAR) with the results of the open approach (OSBAR) as in the Management Of Myelomeningocele Study (MOMS). METHODS This was a systematic comparison of reports on FSBAR with data from the MOMS (n = 78). Inclusion criteria were studies of spina bifida aperta patients who underwent FSBAR and were followed for ≥12 months. Pr...