It has been shown in an earlier paper (Lorber, 1965) dealing with the family history of 722 infants born with spina bifida cystica or encephalocele, that 6 8% of 1256 sibs were also affected, either by the same condition or by the closely allied lesions of anencephaly or congenital hydrocephalus. This high incidence in sibs is suggestive of hereditary factors playing a part in the causation of ...

Radiological records of 104 patients with multiple vertebral anomalies without apparent spina bifida and 112 infants with spina bifida cystica were surveyed and the incidences of hemivertebrae and of rib, vertebral body, and vertebral arch fusions were recorded. The distributions of these four anomalies along the vertebral axis were found not to be statistically different between the two age gr...

It has been shown in an earlier paper (Lorber, 1965) dealing with the family history of 722 infants born with spina bifida cystica or encephalocele, that 6 8% of 1256 sibs were also affected, either by the same condition or by the closely allied lesions of anencephaly or congenital hydrocephalus. This high incidence in sibs is suggestive of hereditary factors playing a part in the causation of ...

The present physical handicaps and social status of 202 survivors of spina bifida cystica attending The Hospital for Sick Children, Great Ormond Street before 1954 are described. Ninety-three of the patients, mostly with uncomplicated meningocele, had escaped serious disability and were living normal lives. But 109 had a serious disability, including three who are mentally retarded. Some of the...

More children with spina bifida cystica are surviving today because of improved operative treatment and clinical care. Problems arising from spinal deformity in these children are presenting more often for treatment. The purpose of this paper is to observe the natural course of kyphotic spinal deformity seen in association with spina bifida cystica. Specific attention is focused on kyphosis bec...

Spina bifida occulta is one form of spinal dysraphism, a term used to refer to imcomplete formation of the midline structure of the dorsum. It is therefore related to all the other forms of spina bifida which have been described under different names, spina bifida aperta or cystica. The basic differences between spina bifida cystica and spinal bifida occulta result from the nature of their orig...

Nicolai Tulp, the physician whose features are immortalized in Rembrandt's painting 'The School of Anatomy', first suggested the name 'spina bifida' (Tulpius, 1652), though the condition was known to Hippocrates, and the mediaeval Arab physicians are said (Denuce, 1906) to have specifically recognized the absence of the spinous processes in the affected area. Ruysch (1691) distinguished between...

Nicolai Tulp, the physician whose features are immortalized in Rembrandt's painting 'The School of Anatomy', first suggested the name 'spina bifida' (Tulpius, 1652), though the condition was known to Hippocrates, and the mediaeval Arab physicians are said (Denuce, 1906) to have specifically recognized the absence of the spinous processes in the affected area. Ruysch (1691) distinguished between...

Nicolai Tulp, the physician whose features are immortalized in Rembrandt's painting 'The School of Anatomy', first suggested the name 'spina bifida' (Tulpius, 1652), though the condition was known to Hippocrates, and the mediaeval Arab physicians are said (Denuce, 1906) to have specifically recognized the absence of the spinous processes in the affected area. Ruysch (1691) distinguished between...