INTRODUCTION ABSTRACT Particle depositional studies from nasal sprays are important for efficient drug delivery. The main influences on deposition involve the nasal cavity geometry and the nasal spray device of which its parameters are controlled by the product design. It is known that larger particle sizes (>>10μm) at a flow rate of 333 ml/s impact in the anterior portion of the nose, leaving ...

Impressive gains have been made in thermal spray coatings through material development and coating parameter selection. Nevertheless, it is usually up to shop personnel to develop a robot program to achieve the final coating. Coating programs are often developed using trial and error. Some motion and deposit analysis programs are available [1], [2]. However, they can be costly and require a lev...

The electrical conductivity and the thermal performance of the films made of reduced graphene oxide (rGO) spray-coated on polycarbonate substrate were investigated. The electrical conductivity and the transmittance of 10 times spray coated film made from the solution with 0.08 wt% of rGO, 0.16 wt% of surfactant were 30 komega/sq and 64%, respectively. The steady-state temperature of the films i...

Using a semi-discrete model that describes the heat transfer of a continuous casting process of steel, this paper is addressed to an optimal control problem of the continuous casting process in the secondary cooling zone with water spray control. The approach is based on the Hamilton–Jacobi–Bellman equation satisfied by the value function. It is shown that the value function is the viscosity so...

     Heat transfer mechanisms and the solidification process are simulated for a continuous casting machine and the geometric shape of the liquid pool is predicted considering different conditions. A heat transfer and solidification model is described for the continuous casting of steel slabs. The model has been established on the basis of the technical conditions of the slab caster in the con...

the spray characteristics of the fuel greatly influence emissions from diesel engines. spray development plays a vital role in improving the combustion and emission characteristics of fuel because it directly affects the air- fuel mixture formation. the spray characteristics of fuel mainly depend on fuel injection process, fuel density, fuel viscosity, ambient pressure and temperature. among th...

piroxicam, an anti-inflammatory drug, exhibits poor water solubility and flow properties, poor dissolution and poor wetting. consequently, the aim of this study was to improve the dissolution of piroxicam. microparticles containing piroxicam were produced by spray drying, using isopropyl alcohol and water in the ratio of 40:60 v/v as solvent system, and spray chilling technology by melting the ...