OBJECTIVE To review the contribution of vesicoureteral reflux and reflux nephropathy to end-stage renal disease. DATA SOURCE Published research articles and publicly available registries. RESULTS Vesicoureteral reflux (VUR) is commonly identified in pediatric patients and can be associated with reflux nephropathy (RN), chronic kidney disease (CKD), and rarely end-stage renal disease (ESRD)....

The patients with renal diseases, especially end-stage renal disease (ESRD), are at high risk of developing cardiovascular disturbances. Some hormones such as brain natriuretic peptide appear to be important serum biomarkers in predicting cardiac death in ESRD patients. Renal diseases cause inflammation, anemia, uremic toxins, fluid overload, and electrolyte disturbance. Kidney transplantation ...

The data provided by the End-Stage Renal Disease (ESRD) Registries documenting a progressive and striking increment over the years of the Hypertension-related ESRD incidence and prevalence support the classic statement that the kidney may be a victim of hypertension. Long-lasting hypertension may induce ESRD in a few patients throught hypertensive nephrosclerosis, particulary in African-America...

One of the most striking features in autosomal dominant polycystic kidney disease (ADPKD) is the difference at onset age of end-stage renal disease (ESRD). Modifier genes may play a role in this phenotypic variability. The mutated nitric oxide synthase 3 gene (NOS3), have a modifier effect on the severity of ADPKD by impairment of NOS3 activity and decreasing of renal vascular nitric oxide prod...

For many years, the development of severe renal disease was a signal of an imminent death. The launch of hemodialysis for the management of end-stage renal disease (ESRD) in March 1960, however, noted a marked change in treatment of ESRD, and subsequently, it’s mortality. Subsequent developments have included peritoneal dialysis, home hemodialysis, and renal transplantation. At present it is po...

INTRODUCTION: Patients with end-stage renal disease (ESRD) may require a panniculectomy in preparation for renal transplantation. ESRD is associated with increased cardiovascular risk factors, electrolyte imbalances, and chronic anemia. These factors may increase the risk of adverse outcomes in patients undergoing panniculectomy. Purpose of this study was to evaluate safety and perioperative co...

Hospitalists and primary care physicians encounter renal disease daily. Although most cases of acute kidney injury (AKI) are secondary to dehydration and resolve by giving fluids, many cases of AKI are due to not uncommon but unfamiliar causes needing nephrology evaluation. Common indications to consult a nephrologist on an emergency basis include hyperkalemia or volume overload in end stage re...

Autosomal dominant polycystic kidney disease (ADPKD) accounted for 4.6% of our end-stage renal disease (ESRD) population. Initial ESRD therapy consisted of hemodialysis in 78% and continuous ambulatory peritoneal dialysis in 22% with significant intertherapy transfers. Half of these patients underwent one or more renal transplantations. Infections, primarily related to ADPKD or ESRD therapy, we...