Trans-stilbenes belong to the group of polyphenolic phytoalexins, and occur in many plant foods. These compounds have received great attention by researchers due to their well-known beneficial health effects. In the present study a chromatographic method that comprises the use of variable wavelength (VWD) and fluorescence (FLD) detectors in series for the analysis of trans-stilbenes is presente...

Stilbenes are dibenzyl polyphenolic compounds produced in several unrelated plant families that appear to protect against various biotic and abiotic stresses. Stilbene biosynthesis has been well described in economically important plants, such as grape (Vitis vinifera), peanut (Arachis hypogaea), and pine (Pinus species). However, very little is known about the biosynthesis and ecological role ...

Stilbenes, especially resveratrol and its derivatives, have become famous for their positive effects on a wide range of medical disorders, as indicated by a huge number of published studies. A less investigated area of research is their antimicrobial properties. A series of 13 trans-resveratrol analogues was synthesized via Wittig or Heck reactions, and their antimicrobial activity assessed on ...

The mechanisms and conditions affecting expression of systemic induced resistance (SIR) in pine are not clearly understood. Two hypotheses were tested here: that SIR against a pathogen induced by either a pathogen or an insect involves coordinated shifts in phloem secondary metabolism; and that fertility affects the production of these compounds. To test these hypotheses, a tripartite system wa...

Candidiasis is a term describing infections by yeasts from the genus Candida, and the type of infection encompassed by candidiasis ranges from superficial to systemic. Treatment of such infections often requires antifungal agents such as clotrimazole, but increased use of these drugs has led to a selection of Candida sp. with increased resistance to these drugs. Antibiotics have been effective ...

Stilbenes are a large group of plant phenolic compounds that have wide range biologically active properties, such as antioxidant, immunomodulatory, anti-inflammatory, and anti-angiogenic effects. In plants, stilbenes involved in the defense against environmental stresses, including fungal infections insect attacks. The biosynthesis is well described for those species where resveratrol its deriv...

Candida albicans is one of the most important fungi associated with oral candidiasis and the treatment of this fungi is a serious problem today because of the resistance of these fungi against conventionally used drugs. So, there is an urgent need of alternative antifungal substances especially from the natural sources. The study was conducted to examine the MFC and time kill activity of two st...

Seven prenylated stilbenes were identified by combined HPLC-PAD-APCI/MSn analysis of an extract of mucilage isolated from peanut (Arachis hypogaea L.) root tips. The principal constituent was assigned the structure 4-(3-methyl-but-1-enyl)-3, 5-dimethoxy-4'-hydroxy-trans-stilbene. The common name mucilagin A is proposed for this novel compound. Its concentration in the mucilage was estimated at ...

Knotweed rhizomes and young sprouts are used in a traditional Asian medicine. Because knotweed rhizomes contain large amount of stilbenes and catechins, the main objective of this study was analysis of selected phenolic compounds, including stilbenes and catechins, in young spring sprouts of the knotweed genus (Japanese knotweed (Reynoutria japonica), Giant knotweed (Reynoutria sachalinensis), ...

Secondary phenolic metabolites are involved in plant responses to various biotic stress factors, and are apparently important for the defense against fungal pathogens. In this study, we investigated their role in defense against the rust Chrysomyxa rhododendri in Norway spruce. The fungal pathogen undergoes a seasonal lifecycle with host shift; after overwintering in rhododendron shrubs, it att...