TriN 2755 is an alkylating antineoplastic agent for intravenous (IV) use, carrying the triazene group as the cytotoxic principal. Using a standard 3 + 3 design, a phase I study was performed in tumour bearing dogs to determine the maximum tolerated dose (MTD), the dose limiting toxicity (DLT), and pharmacokinetic (PK) profile of TriN 2755. Thirty dogs were included in the study. TriN 2755 was a...

Strong environmental gradients can affect the genetic structure of plant populations, but little is known as to whether closely related species respond similarly or idiosyncratically to ecogeographic variation. We analysed the extent to which gradients in temperature and rainfall shape the genetic structure of four Stipa species in four bioclimatic regions in Jordan. Genetic diversity, differen...

The relationship between carbon isotope discrimination (131) of C3 vegetation and long-term (30 years) and short-term (growing period) precipitation was investigated. Different species of Stipa, a dominant grass genus in the (semi-)arid Asian steppes, and other C3 species were collected along aridity gradients in Inner Mongolia in 2005 (11 sites, 71 samples) and in the Republic of Mongolia in 2...

The Stipa grandis steppe is a type of steppe in the Central Asian sub-region, and it is an important resource for livestock production in China. Mowing is one of the main management methods for this steppe. Verifying the response of the Stipa grandis steppe communities to different mowing frequencies is essential for the rational utilization of pastures and the protection and recovery of natura...

New combinations and names are here validated for ten grass (Poaceae) taxa in California for the forthcoming revision of The Jepson Manual. In addition, guided by recent molecular phylogenetic studies, ten non-California grass species are here transferred to Muhlenbergia (Chloridoideae: Cynodonteae) to achieve monophyly of the genus. Lolium, long known to be phylogenetically nested within Festu...

There are tow hierarchically organized of clonal populations are: genetic individuals (genets) can consist of many physiological individuals (ramets). Each ramet takes up resources from its local environment, but the resource pattern can be reorganized within the clone by transport between ramets. According to obsearvation measurement and surveillance of clones and their ramets of caespitose gr...

In data for 5688 ch ildren , age-an d sex-specific com parison s of weigh t, h eigh t, body m ass in dex (BMI), an d skin fold data are m ade with an accepted British stan dard an d also with th e recen tly developed in tern ation al stan dard based on pooled data from several cou n tries. 3 Usin g th ese stan dards, th e au th ors also m ake age-an d sex-specific com parison s across eth n ici...