نتایج جستجو برای: sustained virologic response

تعداد نتایج: 1043902  

2013
Ana Luiza Dias Angelo Lourianne Nascimento Cavalcante Kiyoko Abe-Sandes Taísa Bonfim Machado Denise Carneiro Lemaire Fernanda Malta João Renato Pinho Luiz Guilherme Costa Lyra Andre Castro Lyra

OBJECTIVES Suppressor of cytokine signaling 3, myxovirus resistance protein and osteopontin gene polymorphisms may influence the therapeutic response in patients with chronic hepatitis C, and an association with IL28 might increase the power to predict sustained virologic response. Our aims were to evaluate the association between myxovirus resistance protein, osteopontin and suppressor of cyto...

Journal: :international journal of infection 0
nawfal r hussein department of internal medicine, college of medicine, university of duhok, duhok, iraq; department of internal medicine, college of medicine, university of duhok, duhok, iraq

conclusions if such a regimen is approved, it would be a breakthrough in the treatment of hcv in subjects with hemoglobinopathy. more prospective, randomized control trial studies are needed to investigate the efficacy and safety profile of such a regimen. case presentation we described a 16- year-old male patient with sickle-thalassemia who was infected with a hcv. treatment was started with s...

Journal: :The Journal of infectious diseases 2002
Elisabeth Legrand Didier Neau Tatiana Galperine Pascale Trimoulet Jean-François Moreau Vincent Pitard Jean-Yves Lacut Jean-Marie Ragnaud Michel Dupon Brigitte Le Bail Noëlle Bernard Evelyne Schvoerer Michael Houghton Hervé Fleury Marie-Edith Lafon

CD4 T lymphocyte proliferative responses to hepatitis C virus (HCV) antigens were evaluated before and during an anti-HCV regimen (interferon-alpha2a and ribavirin) in 36 patients coinfected with HCV and human immunodeficiency virus (HIV), to determine whether immune responses against HCV antigens are present in such patients, whether these responses are modified by anti-HCV treatment, and whet...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده پزشکی 1391

مقدمه: ویروس هپاتیت c متعلق به خانواده فلاوی ویریده و از جنس هپاسی ویروس می باشد که عامل بیماری مزمن کبدی در درصدی از افراد مبتلا می باشد. بیماران مبتلا به فرم مزمن بیماری هپاتیت c آلوده شده با ژنوتیپ 1 و 3 برای 48 هفته و ژنوتیپ 2 و 4 برای 24 هفته تحت درمان با انترفرون آلفا و ریباویرین قرار می گیرند. و پس از آن سرم از نظر ژنوم ویروس مورد ارزیابی قرار می گیرد که درصورت منفی شدن سرم از نظر ژنوم، ...

Journal: :The New England journal of medicine 2011
Stefan Zeuzem Pietro Andreone Stanislas Pol Eric Lawitz Moises Diago Stuart Roberts Roberto Focaccia Zobair Younossi Graham R Foster Andrzej Horban Peter Ferenci Frederik Nevens Beat Müllhaupt Paul Pockros Ruben Terg Daniel Shouval Bart van Hoek Ola Weiland Rolf Van Heeswijk Sandra De Meyer Don Luo Griet Boogaerts Ramon Polo Gaston Picchio Maria Beumont

BACKGROUND Up to 60% of patients with hepatitis C virus (HCV) genotype 1 infection do not have a sustained virologic response to therapy with peginterferon alfa plus ribavirin. METHODS In this randomized, phase 3 trial, we evaluated the addition of telaprevir to peginterferon alfa-2a plus ribavirin in patients with HCV genotype 1 infection who had no response or a partial response to previous...

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