Template-directed replication is known to obey a parabolic growth law due to product inhibition (Sievers & Von Kiedrowski 1994 Nature 369, 221; Lee et al. 1996 Nature 382, 525; Varga & Szathmáry 1997 Bull. Math. Biol. 59, 1145). We investigate a template-directed replication with a coupled template catalysed lipid aggregate production as a model of a minimal protocell and show analytically that...

The ribonucleoprotein telomerase synthesizes telomeric DNA by copying an intrinsic RNA template. In most cancer cells, telomerase is highly activated. Here we report a telomerase-based antitumor strategy: expression of mutant-template telomerase RNAs in human cancer cells. We expressed mutant-template human telomerase RNAs in prostate (LNCaP) and breast (MCF-7) cancer cell lines. Even a low thr...

bone like hydroxyapatite (nhap) was synthesized via an in situ biomimetic process in presence of wheat starch. the effect of polymer concentration alteration on the final structure of nhap was investigated. formation of the nhap at room temperature was confirmed by x-ray diffraction (xrd) and fourier transform infrared spectroscopy (ft-ir). size and morphology of the nhap samples were character...

The mechanical stability of commercial GaP/Si templates during thermal annealing and subsequent growth GaP AlGaP using metal-organic chemical-vapour deposition is investigated. Although the as-grown layer template originally presents an excellent surface morphology, at temperatures between 645 ∘C to 845 remove native oxide prior leads plastic relaxation, accompanied by a variety defects, includ...

the in-situ method of synthesis has been used to isolate oxovanadium(iv) complexes with ligands derived by reaction of benzil with amino acids such as glycine, alanine, serine, cysteine and valine, where template effect of vo +2 cation appears to play an important role. the complexes are characterised by elemental analysis, magnetic moment measurements and spectral (infrared, electronic and ele...

cr2o3 nanoparticles were prepared using cr(no3)3.9h2o as starting material, triethanolamine (tea) as template and water as green solvent under microwave irradiation. the products were characterized by x-ray diffraction (xrd), transmission electron microscopy (tem), fourier transform infrared (ft-ir), photoluminescence (pl) and raman spectroscopy. the size distribution of individual particles we...