Common bean ( L.) breeding programs aim to improve both agronomic and seed characteristics traits. However, the genetic architecture of the many traits that affect common bean production are not completely understood. Genome-wide association studies (GWAS) provide an experimental approach to identify genomic regions where important candidate genes are located. A panel of 280 modern bean genotyp...

Many genetic association studies collect a wide range of complex traits. As these traits may be correlated and share a common genetic mechanism, joint analysis can be statistically more powerful and biologically more meaningful. However, most existing tests for multiple traits cannot be used for high-dimensional and possibly structured traits, such as network-structured transcriptomic pathway e...

the current study was designed to estimate the frequency of capn3 and adrb3 genes single nucleotide polymorphisms (snps) and investigate if their polymorphisms have association with estimated breeding values (ebvs) of growth traits in baluchi sheep. phenotypic information about several sheep growth traits on 102 purebred baluchi sheep was collected. association effects of the variants of capn3 ...

Genome-wide association studies (GWASs) at the gene level are commonly used to understand biological mechanisms underlying complex diseases. In general, one response or outcome is used to present a disease of interest in such studies. In this study, we consider a multiple traits association test from the gene level. We propose and examine a class of test statistics that summarizes the associati...

Many genetic association studies on personality traits exist, and several meta-analyses have already been performed: On a serotonin transporter gene polymorphism (5-HTTLPR) and anxiety-related traits. But also other polymorphisms and traits have been examined in meta-analyses. 11, 12 These meta-analyses typically focus on a single personality trait and a single polymorphism. The wiki system pre...

In this study, the potential association of PrP genotypes with ewe reproductive traits and lamb growth traits was investigated. Data were included on ewes and lambs of the INRA 401 breed from the Bourges-La Sapinière INRA experimental farm. This breed was chosen because of good breeding (prolificacy and maternal abilities) and carcass qualities, and the large number of available animals with pe...

The objective of this study was to determine the polymorphism of bovine β-lactoglobulin (β-LG) gene and its association with milk production traits in Iranian Najdi cattle. Blood samples were collected from 80 Najdi cattle from the Najdi cattle breeding station located in Shoshtar, Khuzestan. Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) techniqus were used...

The LEPR is a glycoprotein expressed mainly in hypothalamus, where it takes part in energy homeostasis and in regulation of the activity of the secretory organs. A transition mutation in this gene results in substitution of cytosine by thymine leading to the substitution of threonine by methionine in the intracellular domain of the LEPR-b isoform. This study investigated the impact of polymorph...

Association analysis is a useful method for evaluation of significant association between molecular marker and phenotype of trait. This study was performed to evaluate association between traits related with powdery mildew resistance and molecular markers. This investigation was performed using 77 barley genotypes and AFLP markers. In phenotypic evaluation, reaction of seedlings to powdery mild...

Melanocortin-3 receptor (MC3R) plays an important role in the central control of energy homeostasis, and several functional polymorphisms of this gene have been detected. We have studied MC3R as a candidate gene responsible for variation in economically important traits in chicken. To determine the association between MC3R polymorphism and phenotypic variation, a total of 190 individuals from b...