A 10-month-old female toy poodle was referred to the University of Tokyo Veterinary Medical Center with a urogenital anomaly found during sterilization. An exploratory laparotomy revealed a cyst adhering to the cervix and a unilateral renal agenesis. Histopathology and immunohistochemical analysis of the cyst was consistent with remnants of the Wolffian duct or a Gartner duct cyst. This is a ra...

Objective Multiple pregnancies occur more frequently in assisted reproductive technology (ART) compared to normal conception (NC). It is known that the risk of congenital malformations in a multiple pregnancy are higher than single pregnancy. The aim of this study is to compare congenital malformations in singleton infants conceived by ART to singleton infants conceived naturally. MaterialsAndM...

Hydrometrocolpos is an uncommon congenital disorder consisting of cystic dilatation the vagina and uterus, usually caused by distal obstruction. Many urogenital malformations, ranging from persistent sinus to cloacal dysgenesis, may cause hydrometrocolpos. In obstructive, uterovaginal causes such as imperforate hymen, transverse vaginal septum are common etiologies. Early diagnosis in antenatal...

Congenital malformations of the female genital tract are defined as deviations from normal anatomy resulting poor embryonic development Mulllerian or para-mesonephricducts. The importance these varies greatly depending on stage embryological condition, which can range a simple vaginal septum to total absence utero-vaginal axis. They relatively common and affect around 3-4% women represent 10% c...

OBJECTIVE We aimed to document the reasons of perinatal deaths in a large autopsy series performed in our institute, which is a reference center in the Çukurova region of Turkey. MATERIAL AND METHOD The study included 2150 autopsies performed between January 2000 and December 2012 at our institute. Diagnoses were categorized according to the detected pathologies; congenital malformations were...

Congenital abnormalities are the leading cause of infant mortalities in the United States (25%) and across the world [1]. Public health interventions have included reducing maternal disease, prenatal care of mothers, reduction of exposure to teratogens (agent that can disturb the development of an embryo or fetus), and nutritional interventions [2]. Potentially the most significant nutritional ...

Background: Congenital hypothyroidism (CH), as one of the most common congenital endocrine disorders, may be significantly associated with congenital malformations. This study investigates urogenital abnormalities in children with primary CH (PCH). Methods: This case-control study was conducted on 200 children aged three months to 1 year, referred to Amir-Kabir Hospital, Arak, Iran. One hundred...

Congenital anomalies affecting the ureter-bladder junction are frequent in newborns and are often associated with other developmental defects. However, the molecular and morphological processes underlying these malformations are still poorly defined. In this study, we identified the leukocyte antigen-related (LAR) family protein tyrosine phosphatase, receptor type, S and F (Ptprs and Ptprf [als...

Danforth's short tail (Sd) is a semidominant mutation in mouse affecting the axial skeleton and urogenital system. The notochord is the first visibly abnormal structure in mutant embryos, and disintegrates beginning around embryonic day 9.5 along its entire length, suggesting an essential role for Sd in notochord development and maintenance. Here, we report on the fate of Sd/+ and Sd/Sd cells i...

BACKGROUND Common uterine anomalies are important owing to their impact on fertility, and complex mesonephric anomalies and certain Müllerian malformations are particularly important because they cause serious clinical symptoms and affect woman's quality of life, in addition to creating fertility problems. In these cases of complex female genital tract malformations, a correct diagnosis is esse...