نتایج جستجو برای: کانکسین 30
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زمینه و هدف: ناشنوایی شایع ترین اختلال حسی - عصبی است. حداقل 50% از ناشنوایی ها ارثی بوده و تقریباً نیمی از ناشنوایی های ارثی به صورت اتوزومال مغلوب غیر سندرومی می باشد. جهش در ژن کانکسین 26 (Gap Junction beta2=GJB2) شایع ترین دلیل ناشنوایی غیر سندرمی مغلوب می باشد. جهش نقطه ای delG35، شایع ترین جهش در ژن کانکسین 26 می باشد. این مطالعه با هدف تعیین فراوانی شایع ترین جهش ژن GJB2 به نام delG35 د...
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A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 μg/mL.
The structure of the title salt, C(12)H(12)N(+)·HSeO(4) (-), consists of infinite parallel two-dimensional planes built of 4-benzyl-pyridinium and hydrogen selenate ions that are mutually connected by strong O-H⋯O and N-H⋯O hydrogen bonds. There are no contacts other than normal van der Waals inter-actions between the layers.
We investigated six cases of enterovirus infection in a neonatal unit. The index patient, a 5-day-old boy, was admitted with aseptic meningitis due to echovirus 30 (E30). Secondary infections with E30 occurred in five babies. Comparison of the complete VP1 sequences showed that the isolates recovered from the index patient and his mother were closely related to those recovered from the five bab...
In the title mol-ecular salt, C(4)H(10)NO(+)·C(4)H(5)O(6) (-), the morpholinium cation adopts a chair conformation. The conformation of the C-C-C-C backbone of the monotartrate anion is close to anti [torsion angle = 173.18 (17)°], which is supported by two intra-molecular O-H⋯O hydrogen bonds. In the crystal, the components are linked by N-H-O and O-H-O hydrogen bonds, generating (001) sheets.
In this work a combined molecular dynamics simulation and dynamically corrected transition-state theory (dcTST) study was performed to investigate the effect of interpenetration (catenation) on hydrogen diffusion in metal-organic frameworks (MOFs) as well as their relationships. The results on 10 isoreticular MOFs (IRMOFs) with and without interpenetration show that catenation can reduce hydrog...
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