Kreisman, Stuart H., Anthony Manzon, Sharon J. Nessim, José A. Morais, Réjeanne Gougeon, Simon J. Fisher, Mladen Vranic, and Errol B. Marliss. Glucoregulatory responses to intense exercise performed in the postprandial state. Am J Physiol Endocrinol Metab 278: E786–E793, 2000.—A sevento eightfold increment in hepatic glucose production (endogenous Ra) occurs in postabsorptive (PA) intense exerc...

Evans, Jodi F., James K. Yeh, and John F. Aloia. Osteoblast-like cells of the hypophysectomized rat: a model of aberrant osteoblast development. Am J Physiol Endocrinol Metab 278: E832–E838, 2000.—In a previous work, we demonstrated that the osteoprogenitors derived from the marrow stroma of the hypophysectomized (HX) rat demonstrate enhanced proliferative and differentiation capacities when pl...

Epple, H. J., S. Amasheh, J. Mankertz, M. Goltz, J. D. Schulzke, and M. Fromm. Early aldosterone effect in distal colon by transcriptional regulation of ENaC subunits. Am J Physiol Gastrointest Liver Physiol 278: G718–G724, 2000.— Aldosterone-induced sodium absorption is mediated by the epithelial Na1 channel (ENaC). It is thought that the ‘‘early effect’’ is not based on genomic regulation of ...

Simaan, May, Serge Picard, Jean St-Louis and Michèle Brochu. Functional alteration of dihydropyridinesensitive Ca21 channels in the adrenal glomerulosa of pregnant rats. Am J Physiol Endocrinol Metab 278: E925–E932, 2000.—Our previous work on aldosterone secretion suggested that dihydropyridine-sensitive calcium channels, one type of voltage-dependent calcium channels (VDCC), are functionally i...

Kuemmerle, John F. Endogenous IGF-I regulates IGF binding protein production in human intestinal smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 278: G710– G717, 2000.—Human intestinal smooth muscle in culture produces insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3, IGFBP-4, and IGFBP-5, which modulate the effects of IGF-I. This study examined the regulation o...

STEPHEN M. WIENER,1 ROBERT F. HOYT, JR.,2 JOHN R. DELEONARDIS,2 RANDALL R. CLEVENGER,2 KENNETH R. JEFFRIES,2 KUNIO NAGASHIMA,3 MYRNA MANDEL,4 JENNIE OWENS,5 MICHAEL ECKHAUS,5 ROBERT J. LUTZ,6 AND BRIAN SAFER1 1Molecular Hematology Branch and 2Laboratory of Animal Medicine and Surgery, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda 20892; 3Laboratory of Cell a...

NICOLA L. JONES,1,2,3 AVINASH ISLUR,1 RIZWAN HAQ,4 MARIOLA MASCARENHAS,1 MOHAMED A. KARMALI,2 MARY H. PERDUE,5 BRENT W. ZANKE,4 AND PHILIP M. SHERMAN1,2,3 1Research Institute, Hospital for Sick Children, and Departments of 2Molecular Microbiology and Medical Genetics and 3Pediatrics, University of Toronto, Toronto M5G 1X8; 4Department of Medicine, University of Toronto, Princess Margaret Hospit...

Yamashita, Masatomo, and Mamoru Yamashita. Hyperbaric oxygen treatment attenuates cytokine induction after massive hemorrhage. Am J Physiol Endocrinol Metab 278: E811–E816, 2000.—We investigated the effect of hyperbaric oxygen treatment (HBO) on cytokine induction after hemorrhage, because hypoxia induces cytokines in vitro. Chronically cannulated conscious rats were subjected to 40 ml/kg of he...