Thymocyte growth peptide (TGP) initiates DNA synthesis in immature thymocytes and has previously been characterized as an acidic peptide isolated from calf thymus. We now report the isolation of TGP from sheep thymus and show it to be a nonapeptide with a large N-terminal blocking moiety characterized by high UV absorbance. The amino acid composition is identical to FTS, consisting of 2 Gly, 2 ...

This study evaluated the microhardness and elemental composition of various ceramics immersed in acidic agents. One hundred and five discs of fluorapatite-leucite (IPS d.SIGN) and fluorapatite ceramics (IPS e.max Ceram) were randomly divided into 7 groups of 15 each. Five groups were alternately immersed in acidic agents (citrate buffer solution, pineapple juice, green mango juice, cola soft dr...

The exact role of the central acidic domain of Mdm2 in p53 degradation remains unclear. We therefore performed a systematic and comprehensive analysis of the acidic domain using a series of short deletions and found that only a minor part of the domain was indispensable for Mdm2-mediated p53 ubiquitylation. Moreover, we identified a short stretch of acidic amino acids required for p53 degradati...

Cytosolic glutathione S-transferases were purified from the epithelial cells of human small and large intestine. These preparations were characterized with regard to specific activities, subunit and isoenzyme composition. Isoenzyme composition and specific activity showed little variation from proximal to distal small intestine. Specific activities of hepatic and intestinal enzymes from the sam...

douala metropolitan city loated in the littoral province of cameroon,has experienced a rapid urbaniation and industralisation. the city depends heavily on groundwater as a resource. due to ubiquitous sources of pollution, groundwater quality and contamination has become an imprtant issue for this urban groundwater supply. this study uses the major ion chemistry of groundwater together with t...

Absorption of 808 nm laser light by liposomes containing a pH sensitive, near-infrared croconaine rotaxane dye increases dramatically in weak acid. A stealth liposome composition permits acid activated, photothermal heating and also acts as an effective nanoparticle probe for ratiometric photoacoustic imaging of acidic pH in deep sample locations, including a living mouse.

volcanic rocks of interest are situated in the middle part of the urumieh-dokhtar magmatic arc (udma). they are parts of a vast magmatic province located in the north of bitlis-zagros suture zone. having a prevailing porphyritic texture, these rocks include phenocrysts of plagioclase, amphibole and biotite in a matrix composed of feldspar, quartz, opaque, glass and microlite and mineralogically...

60S ribosomes from encysted gastrulae of the brine shrimp Artemia salina contain two acidic proteins, which are homologous to the Escherichia coli proteins L7 and L12. The proteins were purified and characterized with respect to molecular weight, amino-acid composition, peptide maps, and their functional requirement in the elongation factor dependent binding of aminoacyl transfer RNA to the rib...