ABSTRACT Introduction: Impaired wound healing is a major concern specially in diabetic patients due to unregulated chronic hyperglycemia which further may lead to ulcer, gangrene, and its complications, therefore the development of natural, nontoxic and effective agent is required. we carried out an acute and subacute oral toxicity study on the Cyperus Papyrus (CP) ash in Wistar albino rats. C...

Pistacia vera L., a member of Anacardiaceae family, has been used for sedation and analgesia in traditional medicine. In this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of P. vera leaves were investigated in mice. The antinociceptive activity was studied using hot plate and writhing tests. The effect of the extracts a...

background previous studies have shown that shallomin, one of the active constituents of persian shallot, has a broad range of antimicrobial properties. objectives the safety of shallomin must be established before it can be used in clinical applications. therefore, the aim of the present study was to evaluate the acute toxic effects of shallomin and to estimate its lethal dose low (ldlo) value...

Abstract Background and Objective: Iranian Traditional Medicine (ITM) has a long history in the prevention and treatment of diseases. Clinical uses, side effects, and toxic effects of many singular and compounds were known to scientists of ITM and articular books on toxicology and detoxification of drugs has been written by scientists, but their measurement tools to evaluate chronic toxicity of...

pistacia vera l., a member of anacardiaceae family, has been used for sedation and analgesia in traditional medicine. in this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of p. vera leaves were investigated in mice. the antinociceptive activity was studied using hot plate and writhing tests. the effect of the extracts a...

Background and objectives: Salvia chloroleuca Rech. f. & Allen., is an endemic species growing wildly in north east and center parts of Iran but there is no information about its safety. To provide information about the safety of the species, we evaluated its acute and sub chronic toxicity in rats. Methods: In acute toxicity study, the aqueous methanol (80%) extract at a single dose of...

the toxicity of 7 herbicides to the three cyanobacteria was tested in this work. the results indicated that: (1) there was a highly significant relationship between dried weight or chlorophyll-a and od680nm for tested cyanobacteria; (2) the toxicity of the tested herbicides with the order from high to low was: photosynthesis-inhibiting > accase inhibitor > protox inhibiting herbicides; (3) the ...

Pistacia vera L., a member of Anacardiaceae family, has been used for sedation and analgesia in traditional medicine. In this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of P. vera leaves were investigated in mice. The antinociceptive activity was studied using hot plate and writhing tests. The effect of the extracts a...