Uncontrolled studies have suggested that the newer oral phosphodiesterase inhibitors milrinone and enoximone acutely improve exercise performance in patients with severe chronic cardiac failure. To determine whether an oral placebo presented as an inotropic agent could acutely enhance exercise capacity, two separate groups of stable heart failure patients were studied by serial exercise testing...

Background Previous studies have indicated that ingestion of nitric oxide (NO) supplements prior to exercise may potentially enhance anaerobic performance. Collectively, NO products are marketed to increase energy, strength, stamina and endurance during anaerobic exercise. However, delivery modes and formula combinations of NO supplements differ in regards to other nutrients included (i.e., cre...

BACKGROUND Children and young adults with single-ventricle physiology have abnormal exercise capacity after the Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity. METHODS AND RESULTS This study was a double-blind, placebo-controlled, crossover trial conducted in children and young adults afte...

Background—Children and young adults with single-ventricle physiology have abnormal exercise capacity after the Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow improved cardiac filling and improved exercise capacity. Methods and Results—This study was a double-blind, placebo-controlled, crossover trial conducted in children and young adults after ...

Dietary acid load, quantified as the potential renal acid load (PRAL) of the diet, affects systemic pH and acid-base regulation. In a previous cross-sectional study, we reported that a low dietary PRAL (i.e. alkaline promoting diet) is associated with higher respiratory exchange ratio (RER) values during maximal exercise. The purpose of the present study was to confirm the previous findings wit...

the aim of this study was to compare the effect of a session of aerobic and anaerobic exercise on changes of iga/salivary total protein ratio in non-athlete girls. 36 non-athlete girls were randomly divided into three groups: anaerobic (n =12) with mean age of 23±1.91 years, aerobic (n =12) with mean age of 21±1.45 years and the control group (n =12) with mean age 23.25±2.09 years. salivary sam...

We have recently demonstrated that exercise training can induce important hemodynamic and metabolic adaptations in patients with chronic heart failure due to severe left ventricular dysfunction. This study examines the accompanying changes in submaximal exercise performance and the ventilatory response to exercise in these patients. Before and after 16-24 weeks of exercise training, subjects un...