Amaranthus tricolor Linn. (FamilyAmaranthaceae) popularly known as Joseph’s coat in English. The plant has been used as hepatoprotective and hypoglycemic in Indian system of traditional medicine. In present study the hydroalcoholic extract of leaves of Amaranthus tricolor L. (HAEAT) 100, 200 and 400 mg/kg body weight was studied for anti-nociceptive and anti-inflammatory activities in various a...

Background & Aim: Family Zingiberaceae is worldwide in   distribution. Plants of the zingiberaceae family are used in traditional   herbal folk medicine besides their uses in spices, cosmetic, ornamental, food   preservatives etc. In Uttarakhand the herbs grow from sub-tropical to   temperate region. Globba sessiliflora Simsrhizomes were collected at maturity stage in ...

Background & Aim: Family Zingiberaceae is worldwide in   distribution. Plants of the zingiberaceae family are used in traditional   herbal folk medicine besides their uses in spices, cosmetic, ornamental, food   preservatives etc. In Uttarakhand the herbs grow from sub-tropical to   temperate region. Globba sessiliflora Simsrhizomes were collected at maturity stage in ...

Although there is evidence for the anti-inflammatory activity of nicotinamide, there is no evaluation of its effects in models of nociceptive and inflammatory pain. In addition, there is no information about the potential anti-inflammatory and antinociceptive activities of the nicotinamide isomers, picolinamide and isonicotinamide. Per os (p.o.) administration of nicotinamide (1000 mg/kg, -1h) ...

The aim of this study, evaluate the nociceptive effect adalimumab, a TNF-alpha inhibitor, on formalin-induced inflammatory pain in mice. antinociceptive activity adalimumab was determined adult male BALB-C mice (6 each group) by model and hot plate test applied. Diclofenac, which we used as positive control, showed anti-nociceptive both phases formalin test. at thirtieth minute statistically si...

Plants from the genus Phyllanthus like Phyllanthus muellerianus have long been used in folk medicine for several ailments including fevers, toothache, dysmenorrhea, anemia and paralysis. Despite these folkloric uses, there is little scientific data supporting the use of this plant in the management of pain. The purpose of this study is to evaluate the aqueous extract of the aerial parts of Phyl...

Recent studies have shown that intracerebroventricular administration of cimetidine (CIM) induces anti-nociceptive and anti–inflammatory effects in rats. However, the underlying mechanism of CIM effect has not been determined yet. This study was planned to determine the anti-nociceptive effect of CIM (50 mg/kg, i.p.) in male mice (25-30 g, n = 80) using tail flick test. Also, the role of ATP-se...

objectives this study was designed to evaluate the antinociceptive activity of methanol extract of n. depauperata in male mice. materials and methods the anti-nociceptive activities of the extract were investigated by the formalin test and hot plate test respectively. comparisons between the groups were carried out using one-way analysis of variance (anova), and post hoc tukey test. results n. ...

− The current study aimed to assess some novel pharmacological activities of vanillin. Vanillin inhibited the chick chorioallantoic membrane (CAM) angiogenesis. Vanillin had anti-inflammatory activity using the acetic acid-induced permeability model in mice. Anti-nociceptive activity of vanillin was shown using the acetic acid-induced writhing test in mice. Vanillin inhibited production of nitr...