Background One of the most important cause of severe neonatal hyperbilirubinemia is hemolysis including Rh incompatibility.  The aim of this study was to assess the rate of hyperbilirubinemia due to hemolysis in Rh positive neonates  born to Rh negative mothers. Methods In this retrospective study from March 1998 to February 2003, 60 icteric Rh positive newborns that were born to Rh negative m...

This paper estimates the incremental cost-effectiveness of providing antenatal anti-D prophylaxis in varying dose sizes to either primigravidae or all Rh D negative women. It presents a model for calculating the net cost per 1000 'at risk' women based on the costs of anti-D prophylaxis and the future NHS costs avoided. Incremental cost-effectiveness is measured in terms of the net cost per Rh D...

OBJECTIVES Helicobacter pylori infection occurs worldwide, but the prevalence of this infection varies greatly among different countries and population groups. The aim of this study was to determine the seroprevalence of anti-Helicobacter pylori and anti-cytotoxin-associated gene A (CagA) antibodies in asymptomatic healthy population in the center of Iran and to investigate the relation with di...

Anti-D immunoglobulin is now widely used to prevent Rh-negative mothers from being sensitized by Rh-positive fetal erythrocytes. The administration of anti-D following the transfusion of large amounts of Rh-positive erythrocytes into Rh-negative individuals has been less uniformly successful in preventing primary immunization (Bowman and Chown, 1968), and occasional mild (Woodrow et al, 1968) o...

Anti-D immunoglobulin is now widely used to prevent Rh-negative mothers from being sensitized by Rh-positive fetal erythrocytes. The administration of anti-D following the transfusion of large amounts of Rh-positive erythrocytes into Rh-negative individuals has been less uniformly successful in preventing primary immunization (Bowman and Chown, 1968), and occasional mild (Woodrow et al, 1968) o...

OBJECTIVE To evaluate signs of haemolysis in babies of Rh-D negative mothers who underwent prophylaxis with anti-D immunoglobulin during pregnancy. DESIGN The following were evaluated in all babies of Rh-D negative mothers born within a three month period in our department: haemoglobin level, packed cell volume, mean corpuscular volume, reticulocytes, bilirubin level, and direct Coombs' test ...

Background: When fetal red cells enter the maternal circulation from placenta, an event would be happened that is described as feto-maternal hemorrhage (FMH). This life-threatening condition could be detected by using RBC antigens (surface antigens and intracellular antigens). Therefore, the measurement of fetal RBC in an artificial model would be useful to calculate FMH and consequently the do...

Introduction While the use of elevated middle cerebral artery peak systolic velocity (MCA PSV) in assessing fetal anaemia is well known, its occurrence is uncommon due to the current practice of giving prophylactic doses of ultrafiltered Rh (D) immunoglobulin (anti-D) in Rh (D) negative women. In mothers who do not receive prophylaxis with Rh immunoglobulin, the overall risk of immunisation for...