نتایج جستجو برای: anti tnf
تعداد نتایج: 402081 فیلتر نتایج به سال:
BACKGROUND Anti-tumour necrosis factor [anti-TNF] treatment was demonstrated to have disease-modifying abilities in inflammatory bowel disease [IBD]. In this study, we aimed to determine the effect of anti-TNF treatment timing on IBD disease complications and mucosal healing [MH]. METHODS The following IBD-related complications were tested in relation to timing of anti-TNF therapy start in ne...
Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are idiopathic chronic intestinal inflam-matory diseases, characterized by recurrent episodes of relapse and remission of disease. The introduction of anti-tumor necro-sis factor (anti-TNF) agents has greatly improved the treatment outcomes for IBDs, enabling higher rates of clinical and endo-scopic remission i...
BACKGROUND & AIMS Anti-tumor necrosis factor (anti-TNF) agents are effective treatments for Crohn's disease (CD) and ulcerative colitis (UC). We aimed to determine their patterns of use and changes in these patterns over time, as well as use of immunomodulators and corticosteroids before anti-TNF therapy for persons with inflammatory bowel diseases. METHODS We used the University of Manitoba ...
BACKGROUND Pancreatic ductal adenocarcinoma (PDAC) is one of the most common cancer death reasons. Anti-tumor necrosis factor-alpha (TNF-α) antibodies have shown promising effects in PDAC pre-clinical models. However, the prognostic values of TNF-α, underlying mechanisms by which anti-TNF-α treatments inhibit PDAC, and potential synergistic effects of anti-TNF-α treatments with chemotherapy are...
974, Glass RJ et al.10 Key Point Patients treated with TNF inhibitors remain on therapy long term, suggesting durable effects and tolerability. Anti-TNF Therapy in Biologic-Naïve and Experienced Patients Clinical trials of anti-TNF therapy typically excluded patients who had prior exposure to a TNF inhibitor. In clinical practice, clinicians often encounter patients with RA who have been treate...
Tumor necrosis factor alpha (TNF-α) expression amplifies to excess amounts in several disorders such as rheumatoid arthritis and psoriasis. Although, Anti-TNF biologics have revolutionized the treatment of these autoimmune diseases, formation of anti-drug antibodies (ADA) has dramatically affected their use. The next generation antibodies (e.g. Fab, scFv) have not only reduced resulted immunoge...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید