Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

Background: Human wax is a mixture of desquamated keratinocytes secreted in outer third of the wall of external auditory canal. The wax produced forms a physiological barrier between the external environment and deep external auditory canal. The antibacterial and antifungal properties of human wax due to its chemical composition have raised considerable debate. Different authors have different ...

chemodiversity in plants provides sources of great value which might be helpful for finding new leads in drug discovery programs. fabaceae as the third largest family of flowering plants was chosen to investigate its possible antifungal activity. in order to increase the effectiveness of the result, molecular similarity methods and chemical data were used. twelve plants were selected from fabac...

Cyanobacterial secondary metabolites have a diverse antagonistic activity that lead to disintegration of microbial growth. The study was conducted to evaluate the antifungal property possessed by cyanobacteriaAnabaena variabilis in retarding the growth of plant pathogenic fungal species. It was observed that the extracts prepared from Anabaena variabilis were capable of diminishing the growth a...

Aim: This study was designed to investigate the role of several descriptive structure-activity features in the antifungal drug, amphotericin B and analyze them by artificial neural networks. Method: Artificial neural networks (ANN) based on the back-propagation algorithm were applied to a structure-activity relationship (SAR) study for 17 amphotericin B derivatives with antifungal and membrane ...

In the present study, a new series of 2,6-diaryl-3-methyl-4-piperidones was synthesized by Mannich reaction (condensation) of ethyl-methyl ketone, substituted aromatic aldehydes and ammonium acetate. Oximes and thiosemicarbazone derivatives of 2,6-diaryl-3-methyl-4-piperidones were synthesized by reaction with hydroxylamine hydrochloride and thiosemicarbazide respectively. The chemical structur...