For several years, photodynamic therapy (PDT) has been a treatment option for skin conditions such as nonmelanoma skin cancer. Recently, this technique has been studied for skin infections, particularly those in which biofilms have formed. The antibacterial, immunoregulatory, and regenerative effect of PDT may enable healing of antibioticresistant infections and infections at sites with limited...

This review highlights the possibilities of photodynamic therapy (PDT) using drugs based on chlorin e6, aluminum phthalocyanine, methylene blue as photosensitizers for bacterial and fungal pathologies. method was developed initially to treat tumor diseases, where it had shown its high efficiency safety. Now is actively used in treatment cancers skin, bronchi, stomach, cervix, larynx, or other r...

BACKGROUND Halitosis is a common problem that affects a large portion of the population worldwide. The origin of this condition is oral in 90% and systemic in 10% of cases. The unpleasant odor is mainly the result of volatile sulfur compounds produced by Gram-negative bacteria. However, it has recently been found that anaerobic Gram-positive bacteria also produce hydrogen sulfide (H2S) in the p...

It is generally acknowledged that the age of antibiotics could come to an end, due to their widespread, and inappropriate use. Particularly for chronic wounds alternatives are being thought. Antimicrobial Photodynamic Therapy (APDT) is a potential candidate, and while approved for some indications, such as periodontitis, chronic sinusitis and other niche indications, its use in chronic wounds i...

nowadays, developements in nanotechnology have leeds an increased application of this newborn technology in cancer treatment. in this study, a stabilized micelle was developed to load hpd in order to be used in photodynamic treatment of cancer in an animal model. to construct micelles, pluronic p-105 was used and stabilized to encapsulate hpd . this process includes a 24 h polymerization in whi...

introduction: the efficiency of routine scaling and root planning is negatively influenced by the tooth anatomy and residual bacteria all possibly affecting the treatment outcomes in future. the present study compared the microbiologic effectiveness of the photodynamic therapy (pdt) as an adjunctive treatment modality for nonsurgical treatment in chronic periodontitis. methods: in this randomiz...