in order to achieve a long-lasting effect, one of the main goals in root canal treatment is to eliminate the endodontic bacteria. conventional chemomechanical debridement is considered as the basic treatment in root canal therapy, but adjunctive techniques such as antimicrobial photodynamic therapy (apdt) can also be helpful. the aim of this study was to evaluate reports in the scientific liter...

introduction: deep periodontal pockets pose a great challenge for nonsurgical periodontal treatment. scaling and root planing (srp) alone may not suffice in cases where surgical therapy cannot be undertaken. various recent studies have suggested the use of antimicrobial photodynamic therapy (apdt) for the management of periodontal infections. the aim of this study was to evaluate the effects of...

introduction: the a im of this study is the evaluation of the effect of antimicrobial photodynamic therapy with radachlorin on staphylococcus aureus and escherichia coli. new windows are open in the antimicrobial field so-call photodynamic therapy that incorporates a nonpoisonous photosensitizer (ps) with innocuous special wavelength photons to excite the ps. methods: two strains of bacteria us...

introduction : halitosis is a common problem that affects a large portion of the population worldwide. the origin of this condition is oral in 90% of cases and systemic in 10% of cases. the foul odor is caused mainly by volatile sulfur compounds produced by gram-negative bacteria. however, it has recently been found that anaerobic gram-positive bacteria also produce hydrogen sulfide (h 2 s) in ...

Citation: Cieplik F, Steinwachs V-S, Muehler D, Hiller K-A, Thurnheer T, Belibasakis GN, Buchalla W and Maisch T (2018) Phenalen-1-one-Mediated Antimicrobial Photodynamic Therapy: Antimicrobial Efficacy in a Periodontal Biofilm Model and Flow Cytometric Evaluation of Cytoplasmic Membrane Damage. Front. Microbiol. 9:688. doi: 10.3389/fmicb.2018.00688 Phenalen-1-one-Mediated Antimicrobial Photody...

introduction: elimination of pathological microflora of root canal systems is a major goal in endodontic treatment. this study aimed to compare the antimicrobial efficacy of calcium hydroxide as an intracanal medication and antibacterial photodynamic therapy (apdt) against enterococcus faecalis and candida albicans in teeth with periapical (pa) lesions. methods: this in vivo study was conducted...

Treatment of mucocutaneous and cutaneous Candida albicans infections with photosensitizing agents and light, termed photodynamic therapy (PDT), offers an alternative to conventional treatments. Initial studies using the clinically approved photosensitizer Photofrin demonstrated the susceptibility of C. albicans to its photodynamic effects. In the present study, we have further refined parameter...

Photodynamic therapy has been considered a potential antimicrobial modality against oral infections, including dental caries. A model to estimate the penetration of both photosensitizers and light through human dentin, a factor of interest in photodynamic therapy, is proposed. The photoacoustic spectroscopy technique was used to evaluate in vitro dentin permeability of three different photosens...

Minimization or elimination of antibiotic resistance in microbial species is an urgent need of the present times. Antimicrobial photodynamic therapy is a new therapeutic option through which development of resistance in microorganisms can be avoided. Interest in the use of photodynamic therapy to combat microbial infection is not only linked to the fact that this technique prevents antibiotic r...

Root canal disinfection is one of the main factors governing success of endodontic therapy. Antimicrobial photodynamic therapy (aPDT) is presented as a promising antimicrobial therapy that can eliminate microbiota present in infected root canal systems. In this study, a series of experiments investigated the effects of aPDT on cell viability and biofilm degradation ability of endopathogenic mic...