Decreased tissue blood flow causes pressure ulcers due to prolonged on the area, which becomes problematic for immobile individuals. The medical community has often been involved in curing such a problem individuals with disabilities and immobility. To alleviate this problem, therefore, plenty of investigations are always seeking novel methods. Furthermore, herbal plants increasingly used owing...

INTRODUCTION Osteoarthritis is the most prevalent chronic non-infective joint arthritis. Because of its chronic disease nature, local drugs are preferred due to lower complications. In the present study, the new herbal pomade Marhame-Mafasel for knee osteoarthritis was used in a double-blind crossover trial. The aim of the study was to assess the efficacy and safety of Marhame-Mafasel pomade, w...

Arnebia hispidissima roots have been used traditionally for the treatment of ulcers, boils, cuts, heart ailments and headache, fever, tongue and throat troubles. The purpose of this study was to characterize the most potent phytochemicals present in the ethyl acetate extract having anti-inflammatory and antimicrobial activity using carrageenan and CFA model. The observed results revealed that s...

INTRODUCTION Wound healing is a complex cascade of events with various cellular and biochemical processes that result in reconstruction and regeneration of damaged tissue. The objective of the current study was to scientifically evaluate the medicinal plants said to produce wound healing activity in traditional Iranian medicine (TIM). MATERIAL AND METHODS Electronic databases were searched fo...

Background: There is a growing demand for mass production of shikalkin (a natural pigment consisted of shikonin and alkannin) due to its increasing applications in cosmetics, pharmaceutical and nutrition industries. The root of Iranian Arnebia euchroma produces shikalkin. The promising capability of this plant for shikalkin production has already been demonstrated in cell culture studies. Obje...

BACKGROUND: Epidermolysis bullosa (EB) is a skin fragility disorder that results in the disruption of dermo-epidermal junction and painful blisters on mucous membranes. Currently, there almost no definite treatment for EB patients. AIM: This study aims to assess effect topical formulation based Arnebia euchroma (AE) lesions induced by EB. MATERIALS AND METHODS: All patients with diseases treate...