atherosclerosis is the leading cause of death in most parts of the world. this disorder affects mostly patients above the age 40 years. this case report introduces a 17 years old girl with early development of coronary artery disease who had severe coronary atherosclerosis that did not respond to medical and interventional treatment and underwent surgical operation in cardiac surgery department...

Background and Aim: Oral infections are usual between people of any age and can activate systemic inflammation. The microbiota consists of a variety of microorganisms that play an important role in metabolism, immune function, and homeostasis. Oral microbiota in human atherosclerotic plaques has been identified by various techniques. Therefore, the focus of study was to determine the correlatio...

Atherosclerosis is one of the most significant threats to health middle-aged and elderly people. The incidence rate atherosclerosis has been climbing its mechanism remains unclear. aim was determine role ankyrin repeat domain 36 in atherosclerosis. In mice aortic endothelial cells models stimulated by lipopolysaccharide, I found that Ankrd36 overexpression decreased expression inflammation fact...

Chemokines and their receptors represent a potential target for immunotherapy in chronic inflammation. They comprise large family of cytokines with chemotactic activity, cognate are expressed on all cells the body. This network dictates leukocyte recruitment activation, angiogenesis, cell proliferation maturation. Dysregulation chemokine receptor expression as well function participates many pa...

Cytomegalovirus (CMV) infection is one of the most common infections that affects humans’ cardiovascular system. Although the literature includes controversial evidence for any correlation between CMV infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. However, the number of prospective...

objective(s): atherosclerosis is a chronic immune-inflammatory disease that generally leads to ischemic heart disease. ghrelin has several modulatory effects on cardiovascular system. in this study, we investigated the effect of ghrelin on aortic intima-media thickness, size and the number of adipocyte cells in obese and control mice. materials and methods:this study was conducted on 24 male c5...

Atherosclerosis has been linked to cognitive decline in late life; however, the impact of cardiovascular risk factors (CVRFs) and subclinical atherosclerosis on brain metabolism at earlier stages remains unexplored. This study sought determine association between metabolism, atherosclerosis, CVRFs middle-aged asymptomatic individuals. included 547 participants (50 ± 4 years, 82% men) from PESA ...

Abstract Purpose Whether antiphospholipid antibodies (aPLs) cause atherosclerosis in certain arteries with specific compositions and locations remains unknown. We investigated the relationship between aPLs their association of abdomen lower extremities. Methods Of 2273 patients, 697 who underwent computed tomography angiography extremities aPL evaluation were included. Atherosclerosis distribut...