We study the modification of Altarelli-Feruglio $A_4$ flavor symmetry model by adding three singlet flavons $\xi'$, $\xi''$ and $\rho$ is augmented with extra $Z_2\times Z_2^ \prime$ to prevent unwanted terms in our study. The addition these lead two higher order corrections form perturbation parameters $\epsilon$ $\epsilon^\prime$. These yield deviation from exact tri-bimaximal (TBM) neutrino ...

Abstract This paper presents a bi-objective model for the design and optimization of sustainable hierarchical multi-modal hub network. The proposed focuses on sustainability by considering economic, environmental, social aspects decisions in A case Turkish network freight transportation is used to validate model. To solve small-sized problems, augmented epsilon constraint method version 2 (AUGM...

We propose an inexact proximal augmented Lagrangian framework with explicit inner problem termination rule for composite convex optimization problems. consider arbitrary linearly convergent solver including in particular stochastic algorithms, making the resulting more scalable facing ever-increasing dimension. Each subproblem is solved inexactly and self-adaptive stopping criterion, without re...

In this paper, we introduce the notion of ($epsilon $, $epsilon $ $vee$ q_{k})− fuzzy subnear-ring which is a generalization of ($epsilon $, $epsilon $ $vee$ q)−fuzzy subnear-ring. We have given examples which are ($epsilon $, $epsilon $ $vee$ q_{k})−fuzzy ideals but they are not ($epsilon $, $epsilon $ $vee$ q)−fuzzy ideals. We have also introduced the notions of ($epsilon $, $epsilon $ $vee$ ...

An immunotherapeutic vaccine for allergy was produced by designing IgE-based synthetic peptide immunogens and selecting them for functional immunogenicity. The vaccine targets the binding site on IgE for the high affinity receptor Fc epsilon RI, by active immunization. The peptide target site on IgE heavy chain was selected from among the amino acid sequences for the C epsilon 2, C epsilon 3, a...

Network representation can reveal the topological dysfunctions of brain function [1]. Recently brain network construction of whole brain voxels has been introduced using the epsilon neighbor method [2, 3]. However, this method has a difficulty in regional network interpretation. Thus we propose the voxel-based network construction on gray matter of FDG-PET image via the epsilon neighbor method ...

Although ethanol abuse is the most common cause of pancreatitis, the mechanism of alcohol's effect on the pancreas is not well understood. Previously, we demonstrated that in vitro ethanol treatment of pancreatic acinar cells augmented the CCK-8-induced activation of NF-kappaB, a key signaling system involved in the inflammatory response of pancreatitis. In the present study, we determine the r...

This paper discusses methods for generating or approximating the Pareto set of multiobjective optimization problems by solving a sequence of constrained single-objective problems. The necessity of determining the constraint value a priori is shown to be a serious drawback of the original epsilon-constraint method. We therefore propose a new, adaptive scheme to generate appropriate constraint va...

This paper presents a scheme for generating the Pareto front of multiobjective optimization problems by solving a sequence of constrained single-objective problems. Since the necessity of determining the constraint value a priori can be a serious drawback of the original epsilon-constraint method, our scheme generates appropriate constraint values adaptively during the run. A simple example pro...