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AIMS To evaluate the proliferative activity of urothelial neoplasms, compare it with that of the normal urinary tract epithelium, and determine its relation to morphological grade and presence of invasion. METHODS Multiple biopsy specimens from 53 individuals--eight normal controls, five patients with severe urothelial atypia, and 40 with transitional cell carcinomas (TCCs)--were studied usin...

Generally, an industrial product has more than one quality characteristic. In order to establish performance measures for evaluating the capability of a multivariate manufacturing process, several multivariate process capability indices have been developed based on the assumption of normality. Quality characteristics of many manufacturing processes in the chemical, pharmaceutical and electronic...

We previously reported that type 2 diabetes risk, early impaired glucose tolerance and insulin resistance can be predicted by measuring the fasting levels of certain biomarkers. Here we validated these findings in randomly recruited healthy volunteers (n = 101) based on biomarker expression as well as various non-invasive indices. Weight, body mass index, waist circumference and visceral fat di...

A series of 2,389 Emergency Department surgical admissions was assessed for quantitative indices of actual services rendered and time spent. Auto accident-related patients were compared to other Emergency Department surgical patients. The average diagnostic index for auto accident patients was 48 units compared to 25 units for all patients. Their workload for Emergency Department personnel was ...

The capability analysis of production processes where there are more than one correlated quality variables is a complicated task. The problem becomes even more difficult when these variables exhibit non-normal characteristics. In this paper, a new methodology is proposed to estimate process capability indices (PCIs) of multivariate non-normal processes. In the proposed methodology, the skewness...

In today’s competitive business and industrial environment, it is becoming more crucial than ever to assess precisely process losses due to noncompliance to customer specifications. To assess these losses, industry is extensively using Process Capability Indices for performance evaluation of their processes. Determination of the performance capability of a stable process using the standard proc...

The autologous mixed lymphocyte reaction (auto-MLR) measures the ability of non-T cells to stimulate autologous T cells to proliferate in tissue culture. The auto-MLR was studied in 1 1 patients with autoimmune thrombocytopenic purpura (ATP). Seven patients had decreased auto-MLR. which averaged 4440 ± 3364 cpm (SEM) compared to 1 5.360 ± 6905 cpm for simultaneously studied controls. The averag...