background: the h9n2 subtype of influenza a viruses is considered to be widespread in poultry industry. adamantane is a group of antiviral agents which is effective both in prevention and treatment of influenza a virus infections. these drugs inhibit m2 protein ion channel which has role on viral replication. objectives: the main objective of this study is to evaluate m gene of avian influenza ...

BACKGROUND Avian influenza viruses represent a growing threat of an influenza pandemic. The co-circulation of multiple H9N2 genotypes over the past decade has been replaced by one predominant genotype-G57 genotype, which displays a changed antigenicity and improved adaptability in chickens. Effective H9N2 subtype avian influenza virus vaccines for poultry are urgently needed. OBJECTIVE In thi...

materials and methods a total of 300 day-old broiler chicks (ross 308) divided into three equal groups (1 to 3) .the chicks in group 1 were immunized with killed aiv h9n2. the chicks in group 2 were infected with ai virus subtype h9n2. the chicks in group 3 were kept as controls and did not receive any vaccined or lived virus. chicks sera were collected at day 42 usingrns1-elisa and commercial ...

Avian influenza viruses are currently one of the main threats to human health in the world. Although there are some screening reports of antibodies against these viruses in humans from Western countries, most of these types of studies are conducted in poultry and market workers of Asian populations. The presence of antibodies against avian influenza viruses was evaluated in an elderly European ...

Sequence analysis and phylogenetic study of hemagglutinin (HA) gene of H9N2 subtype of avian influenza virus isolates (outbreaks of 1998-2002) in Tehran province (Iran) were studied. Two sets of forward and reverse primers in highly conserved regions, based on sequences of HA gene in Genbank, were designed. PCR products of a 430-bp fragment of 16 isolates were sequenced and then were aligned wi...

Avian influenza virus (AIV) H9N2 is endemic in Iran and its large-scale circulation in the poultry industry of the country is devastating. This virus was first reported in the industrial poultry populations of Iran in July 1998. Some of the published studies showed that inactivated avian influenza (AI) vaccines are capable of inducing an immune response and providing protection against morbidit...

influenza a viruses possesses two virion surface glycoproteins including haemagglutinin (ha) and neuraminidase (na). the na plays an important role in viral replication and promotes virus release from infected cells and facilitates virus spread throughout the body. to find out any genomic changes that might be occurred on na gene of avian influenza circulating viruses, we have genetically analy...

I N T R O D U C T I O N Avian influenza (AI) (Orthomyxoviridae) is a well-known viral disease that affects birds worldwide. In recent years, highly pathogenic avian influenza (HPAI) has re-emerged worldwide, raising concern in human and veterinary health authorities. Avian influenza has been reported in many countries from the Middle East region. In Pakistan outbreaks of HPAI H7N3 subtype occur...

In China, H9N2 subtype avian influenza outbreak is firstly reported in Guangdong province in 1992. Subsequently, the disease spreads into vast majority regions nationwide and has currently become endemic there. Over vicennial genetic evolution, the viral pathogenicity and transmissibility have showed an increasing trend as year goes by, posing serious threat to poultry industry. In addition, H9...