Pseudomonas aeruginosa is one of the most common causes of keratitis. The current study was done to evaluate the therapeutic effects of antibacterial combinations with Silver nanoparticles (Ag-NPs) and Ciprofloxacin in experimental Pseudomonas keratitis. Sixty four New Zealand rabbits were prepared. All rabbits were randomly categorized into eight groups (each group containing eight rabbits): C...

purpose: to report a case of bilateral acanthamoeba keratitis with recurrence after keratoplasties case report: here we report a case with bilateral acanthamoeba keratitis who initially responds to medical treatment, after discontinuation of treatment the disease flared up and not responded to medical therapy so superficial keratectomy was done and medical treatment continued and the ulcer impr...

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...

PURPOSE To describe the results of therapeutic penetrating keratoplasty in patients with impending perforation or perforated infectious keratitis. METHODS Fifty-nine charts of patients with infectious keratitis who were submitted to therapeutic penetrating keratoplasty were retrospectively reviewed at the Department of Ophthalmology of the Santa Casa of São Paulo from January 2000 to December...

The clone library method using PCR amplification of the 16S ribosomal RNA (rRNA) gene was used to identify pathogens from corneal scrapings of C57BL/6-corneal opacity (B6-Co) mice with bacterial keratitis. All 10 samples from the eyes with bacterial keratitis showed positive PCR results. All 10 samples from the normal cornea showed negative PCR results. In all 10 PCR-positive samples, the predo...

purpose: to report the clinical, confocal scan, and histopathologic features of bilateral nocardia keratitis following photorefractive keratectomy (prk). case report: a 23-year-old girl underwent simultaneous bilateral prk for myopia. on the third postoperative day, dense central infiltrates mainly involving the anterior stroma were noticed in both eyes. clinical and confocal scan features were...

PURPOSE OF REVIEW Topical corticosteroid use in the setting of infectious keratitis has been a controversial issue. The aim of this review is to provide an update on the evidence for use of topical corticosteroids in addition to antibiotics in bacterial keratitis. RECENT FINDINGS Judicious use of steroids is postulated to limit the inflammatory component of bacterial keratitis, but can theore...

Background: To explore the prevalence of lacrimal duct obstruction in patients with infectious keratitis, and the necessity of lacrimal duct dredge in the treatment of human infectious keratitis. Methodology/Principle Findings: The design is prospective, non-control case series. Thirty-one eyes from twenty-eight continuous patients with infectious keratitis were included in this study. The pres...

Introduction Contact lens wearing has been increased globally during recent decades, which is one of the main risk factors for developing microbial keratitis. Microbial keratitis a severe and dangerous condition that causes cornea inflammation. It can lead to corneal scarring perforation or even endophthalmitis visual loss if it remains untreated. Among bacterial, fungal, protozoal, viral agent...