«bladder»
۵۸٬۱۴۲ نتیجهTreatment with Low-Dose Interferon- Restores the Balance between Matrix Metalloproteinase-9 and E-Cadherin Expression in Human Transitional Cell Carcinoma of the Bladder
Tumor invasion and metastasis are regulated by the expression of genes such as E-cadherin, which regulates cell adhesion, and matrix metalloproteinase-9 (MMP-9), which alters the integrity of the extracellular matrix. Both up-regulation of MMP-9 and down-regulation of Ecadherin c
Urodynamic findings of the painful bladder syndrome/interstitial cystitis: a comparison with idiopathic overactive bladder.
PURPOSE In this study we identify the characteristics of the urodynamic results in patients with painful bladder syndrome/interstitial cystitis and in those with idiopathic overactive bladder. MATERIALS AND METHODS The fluoroscopic urodynamic study results were analyzed retrospec
Stem Cell Therapy in Bladder Dysfunction: Where Are We? And Where Do We Have to Go?
To date, stem cell therapy for the bladder has been conducted mainly on an experimental basis in the areas of bladder dysfunction. The therapeutic efficacy of stem cells was originally thought to be derived from their ability to differentiate into various cell types. Studies abou
Inhibition of Tumorigenicity and Metastasis of Human Bladder Cancer Growing in Athymic Mice by Interferon- Gene Therapy Results Partially from Various Antiangiogenic Effects Including Endothelial Cell Apoptosis
We determined whether the IFNgene could suppress angiogenesis, tumor growth, and metastasis of human bladder transitional cell carcinoma. The highly tumorigenic and metastatic 253J B-V human bladder transitional cell carcinoma (TCC) cell line (resistant to the antiproliferative e
Bladder reduction surgery accelerates the appearance of spontaneous voiding in neonatal rats.
PURPOSE Patients with nocturnal enuresis may have small functional bladder capacity or altered bladder fullness sensation. We determined whether reducing bladder volume would affect the central inhibition of voiding that is normally present between birth and 2 weeks of life in ne
AB320. SPR-47 Monitoring nerve activity during bladder filling in a rat model
Objective: Surgical rerouting of neuronal pathways may allow functional reinnervation of the bladder. We aim to develop techniques to monitor afferent (sensory) nerve activity during bladder filling in normal intact bladders for eventual application to monitoring sensory reinnerv
Hodgkin's lymphoma presenting as a bladder tumour.
Sir: Lymphoma of the urinary bladder is a rare tumour, accounting for less than 1% of malignant bladder lesions. It may occur as a disease localized to the bladder (primary bladder lymphoma), as the site of first evidence of a disseminated disease (non-localized bladder lymphoma)
Intravesical Therapy for Superficial Bladder Cancer
The intravesical instillation of therapeutic agents for the treatment of localized bladder cancer began in 1903 when Herring[1] summarized his experience with silver nitrate. Since then, intravesical chemotherapy and immunotherapy have emerged as effective adjuncts to endoscopic
Adenovirus-mediated Delivery of p16 to p16-deficient Human Bladder Cancer Cells Confers Chemoresistance to Cisplatin and Paclitaxel1
We have previously established the efficacy of adenoviral gene delivery vectors for the treatment of bladder carcinoma in vivo. In the present work, we developed a gene therapy strategy for bladder cancer based on the replacement of the tumor suppressor pi6, which is known to be
Influence of sildenafil on blood oxygen saturation of the obstructed bladder
BACKGROUND Blood oxygen saturation (BOS) is decreased in a low-compliant, overactive obstructed bladder. The objective of this study is to determine the effect of Sildenafil (SC) on bladder function and BOS) in an in vivo animal model of bladder outlet obstruction. METHODS Thirty