The oedema which forms around an intracerebral haemorrhage has a complex aetiology. The immune response may have a role in its formation. There is clinical and experimental evidence that circulating leucocytes and platelets may mediate oedema formation. Global depletion of circulating leucocytes and platelets by whole body irradiation in a rodent model of intracerebral haemorrhage was found to ...

infiltrates. His clinical condition rapidly normalised over the next few hours, and a repeat chest radiograph at 48 h was normal. Transthoracic echocardiography, renal and brain imaging were normal. The diagnosis is most consistent with negative pressure pulmonary oedema, also known as post-obstructive pulmonary oedema. This is caused by repeated, very forceful inspiratory manoeuvres against an...

OBJECTIVES Our previous experiments proved that methylprednisolone (MP) can significantly reduce axonal impairment accompanying extracellular oedema induced by the osmotic challenge (load) on the blood-brain barrier (BBB). The aim of the present work was to identify whether MP can affect myelin impairment accompanying intracellular oedema induced by water intoxication. METHODS For induction o...

Posterior Reversible Encephalopathy Syndrome (PRES) is an emergency medical condition with varied aetiology, presentation and outcomes reported in literature. It presents clinically as reversible subcortical vasogenic brain oedema caused by endothelial injury resulting from abrupt changes blood pressure or direct effects of cytokines on endothelium damage to barrier excessive exudation parenchy...

In this report, a case of adult onset fatal cerebral oedema as a rare complication of diabetic ketoacidosis (DKA) is described and confirmed at post-mortem pathological examination. The pathogenesis of cerebral oedema due to DKA is still unknown. Potential mechanisms include the administration of sodium bicarbonate leading to intracellular acidosis, excessive fluid infusion causing swelling of ...