Background: We compared 3D-conformal radiation therapy (3D-CRT) and intensity-modulated (IMRT) planning for left-sided post-mastectomy patients. Aim: To compare the dose coverage of target volume (PTV) delivered to organs at risk (OAR) 3D-CRT IMRT plans. Setting: Department Oncology, central South Africa. Methods: Twenty-six archived CT scans patients with breast cancer were included. The plans...

results no correlation between as and history of rt, rt-to-follow-up time interval, laterality of bc, framingham’s 10-year risk score or traditional cad risk factors were detected. increase in cacs related to the senile atherosclerotic process was shown (p < 0.001). conclusions no difference between cacs was noted between bc patients with a history of 3d-crt and the non-bc women without a histo...

Abstract Cancer cell spheroids are the simplest 3D in vitro cancer models and have been extensively used for research. More recently, becoming complex, with introduction of a matrix non-cancer types to mimic specific tumour aspects. However, applying drugs or agents matrix-embedded can be problematic. Most matrices impede also bind visualizing non-specifically, vicinity embedded spheroids. This...

objective(s): radiation therapy for breast cancer can induce myocardial capillary injury and increase cardiovascular morbidity and mortality. a prospective cohort was conducted to study the prevalence of myocardial perfusion abnormalities following radiation therapy of left-sided breast cancer patients as compared to those with right–sided cancer. methods: to minimize potential confounding fact...

Objective(s): Radiation therapy for breast cancer can induce myocardial capillary injury and increase cardiovascular morbidity and mortality. A prospective cohort was conducted to study the prevalence of myocardial perfusion abnormalities following radiation therapy of left-sided breast cancer patients as compared to those with right–sided cancer. Methods: To minimize potential confounding fact...

In our study, we aimed to measure the dose exposed by fetus during three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated (IMRT) treatment techniques in pregnant patients who had undergo due breast cancer with thermoluminescence dosimetry (TLD) compare these measurements planning system (TPS). 2.5 mm- thick computed tomography (CT) images of Alderson Rando phantom device were...

PURPOSE To quantify the potential advantages of prone position breast radiotherapy in terms of the radiation exposure to out-of-field organs, particularly, the breast or the lung. Several dosimetric studies have been reported, based on commercial treatment planning software (TPS). These TPS approaches are not, however, adequate for characterizing out-of-field doses. In this work, relevant out-o...

PURPOSE To report on local control and survival after breast conserving therapy (BCT) including three-dimensional conformal simultaneous integrated boost irradiation (3D-CRT-SIB) and on the influence of age on outcome. PATIENT AND METHODS For this study, 752 consecutive female breast cancer patients (stages I-III), treated with 3D-CRT-SIB at the University Medical Center Groningen from 2005 t...

Introduction: The aim of this study was to evaluation radiobiological modeling parameters on tumor control probability (TCP) for prostate cancer in three different models. These parameters included α⁄β ratios and cell surviving fraction at 2 Gy (SF2). Materials and Methods: The Poisson, equivalent uniform dose (EUD) and linear quadratic (LQ) models was used as...

background: we aimed to compare field-in-field technique (fif) with conformal tangential field radiotherapy (crt) in terms of dosimetric benefits for early stage breast cancer radiotherapy. materials and methods: twenty consecutive left-side breast cancer patients who underwent breast-conserving surgery were included to the study. for each patient, two different treatment plans were created for...