human herpes virus 8 (hhv8) causes kaposi’s sarcoma, a common cancer among aids patients. it is proposed that this virus plays a role in formation of some blood vessel and lymphoma tumors. this study aimed to investigate the frequency of kshv among benign and malignant breast tumors. a total of 24 carcinomas and 24 fibroadenomas paraffin embedded tumoral tissue samples were obtained from the pa...

background: a hemangioma is a rather common benign soft tissue tumor that rarely originates from both the pectoralis muscle and the breast. vascular tumors of the breast, such as benign hemangiomas, are rarely seen in men. case presentation: a 40-year-old man presented with a non-tender palpable right breast mass since 6 months ago. on physical examination, a hard lump was detected in the centr...

Introduction: N-nitroso-N-methylurea (NMU) is a carcinogen from nitrosamines family, which has been used to induce breast cancer in rodents. This model of breast cancer is very similar to the estrogen dependent breast cancer in human. As a continuation of our recent works, in the present study, the expressions of both p53 and p27 were investigated in NMU-induced breast cancer in Wistar Albin...

the primary carcinoma may secondarily invade bone tissue through direct extensions, blood circulation or lymphatic transportation particulary when it is arising from breast, prostate, kidney, thyroid and lung. metastatics tumors of bone are more common than primary tumor of bone. the most common tumor, which metastasizes into bone, is the breast adenocarcinoma. some metastatic tumors of bone in...

background: the female breast is subjected to a lifetime of hormonal controls, whose effect is evident at the time of menarche and during the menstrual cycle, pregnancy and lactation. studies have reported multiple risk factors for breast cancer, some of which are a reflection of hormonally mediated events. the steroid receptors are also served as prognostic factors for evaluating status of mal...

Background: The female breast is subjected to a lifetime of hormonal controls, whose effect is evident at the time of menarche and during the menstrual cycle, pregnancy and lactation. Studies have reported multiple risk factors for breast cancer, some of which are a reflection of hormonally mediated events. The steroid receptors are also served as prognostic factors for evaluating status of mal...

introduction: breast cancer is the most common of all malignant neoplasms in women worldwide. this study aims to demonstrate certain biological, clinical and pathological characteristics of patients treated at the university hospital oncology unit. methods: a descriptive study was conducted during a period of 2 years, from october 2003 through september of 2005 in kermanshah, iran. 555 patients...

the mitochondrial dna (mtdna) mutations in mitochondrial coding and non coding regions seem to be important in carcinogenesis. the aim of this investigation was to evaluate coding region (mt-trnaphe and trnapro) and non-coding sequence, mitochondrial displacement loop (mtdna d-loop), in the cancerous and non-cancerous lesions of iranian patients with breast cancer (bc). genomic dna was extracte...

the majority of osseous tumors of the hand are benign. the surgeon who evaluates and treats osseous tumors of the hand has to be familiar with limb anatomy, tumor biology, various presentations of the tumors and the range of treatment possibilities and their limitations. lesions in the hand more often present earlier in their course than those at other sites, just because they are more likely t...