Reyhane Hoshyar

Department of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran

[ 1 ] - Anti-proliferative and apoptotic effects of Ziziphus Jujube on cervical and breast cancer cells

Objectives: Ziziphus Jujube (Jujube) plant has exhibited numerous medicinal and pharmacological properties including antioxidant and anti-inflammatory effects. This study was carried out to investigate its anti-cancer and pro-apoptotic abilities in human cervical and breast cancer cells in vitro. Materials and Methods: The cervical OV2008 and breast MCF-7 cancer cells were incubated with differ...

[ 2 ] - راهکارهای تغذیه ایی موثر بر پیشگیری از بروز سرطان معده

Introduction: Gastric cancer is the second leading cause of cancer-related mortality worldwide and is yet increasing in Asian countries such as Iran. Despite using chemotherapy for the treatment, its 5-year survival is only about 20%. Thus, the complementary therapy and prevention are the main efforts for its control. In this review article, we attempt to describe the eefective strategies for p...

[ 3 ] - خواص ضدسرطانی کلاله گیاه زعفران (کروکوس ساتیووس)

Background: Nowadays one of the most common causes of death is cancer worldwide, which its incidence and mortality rate dramatically increasing in Iran. Saffron herb is locally grown in South Khorasan. The present study reviewed the anticancer properties of saffron stigma on various macromolecule, cell, and animal models. In traditional medicine saffron herb treated many diseases including diab...

[ 4 ] - Investigation of p53 and p27 expressions in the N-nitroso-N-methylureainduced breast cancer in female Wistar Albino rats

Introduction: N-nitroso-N-methylurea (NMU) is a carcinogen from nitrosamines family, which has been used to induce breast cancer in rodents. This model of breast cancer is very similar to the estrogen dependent breast cancer in human. As a continuation of our recent works, in the present study, the expressions of both p53 and p27 were investigated in NMU-induced breast cancer in Wistar Albin...

[ 5 ] - مکانیسم‌های اپی‌ژنتیک و نقش آنها در بروز و درمان سرطان: مطالعه مروری

Both genetic and epigenetic changes are effective in cancer incidence and development. . .Epigenetic processes are alternations of DNA and histones conformations, chromatin remodeling, DNA methylation, post-translational modifications of histones and microRNAs patterns which are associated with genes expression or inhibition of them in cells. Some of reversible epigenetic changes such as DNA an...