In this research, one-pot three-component synthesis of 3,4-dihydropyrimidin-2-(1H)-ones havebeen developed using Biginelli reaction from the interaction between ethyl/methyl acetoacetate,aromatic aldehydes, and urea/thiourea in the presence of 4-sulfobenzoic acid as a new, effective,inexpensive, and available bronsted acid. Avoidance of toxic and dangerous solvents, easy isola...

The history of assessing the acid-base equilibrium and associated disorders is intertwined with the evolution of the definition of an acid. In the 1950s clinical chemists combined the Henderson-Hasselbalch equation and the Bronsted-Lowry definition of an acid to produce the current bicarbonate ion-centred approach to metabolic acid-base disorders. Stewart repackaged pre-1950 ideas of acid-base ...

Abstract Depletion of fossil fuels resources has triggered more research on finding potential alternative sources that are sustainable such as biomass waste. However, deconstruction the complex waste into desired products is too challenging and usually require a strong catalyst with great hydrolysing property. Common acids sulphuric acid, hydrochloric acid nitric were most studies for conversio...

The adsorption of pyridine on a complete monolayer molybdenum oxide-Al203 catalyst was studied. Both Lewis and Bronsted acid sites are present on a catalyst with a Mo valence of -4.1. The orientation of adsorbed pyridine was studied by means of its interaction with surface OD groups, which leads to the formation of only 2-deuteriopyridine. The fraction of molybdenum ions active for hydrogenatio...

In the present investigation, we describe the synthesis of β-amino alcohols from a medium chain fatty acid, 10-undecenoic acid and evaluation of their cytotoxicity. Nucleophilic ring opening reactions of epoxy undecanoates of varying ester chain lengths (C1-C8) with aniline in equimolar ratio (1:1) was carried out using Bronsted acidic ionic liquid, 1methylimidazolium tetrafluoroborate, thus pl...

Silica Vanadic Acid, SVA, (oxo-vanadium has been supported on silica) as a dual Lewis and Bronsted acid ability was prepared and efficiently catalyzed one-pot multi-component condensation of enolizable ketones or alkyl acetoacetates with aromatic aldehydes, acetonitrile and acetyl chloride. The described reaction was produced β-acetamido ketone or ester derivatives in high to excellent yields i...

Cdc25 phosphatases are dual specificity phosphatases that dephosphorylate and activate cyclin-dependent kinases (CDKs), thereby effecting the progression from one phase of the cell cycle to the next. Despite its central role in the cell cycle, relatively little is known about the catalytic mechanism of Cdc25. In order to provide insights into the catalytic mechanism of Cdc25, we have performed ...

The review is dedicated to the topical field of research aimed at creating catalysts combining several types active sites. At same time, composition Fischer–Tropsch synthesis (FTS) products can be controlled by changing strength and concentration sites inter-site distances. A comparative analysis literature data allows formulate main principles catalytic particles formation in FTS acid-catalyze...