ATP-dependent chromatin remodeling enzymes, such as SWI/SNF, hydrolyze thousands of ATPs to regulate gene expression on chromatin fibers. Recent mechanistic studies suggest that these enzymes generate localized changes in DNA topology that drive formation of multiple, remodeled nucleosomal states.

In this research a final element model for simulating three dimensional deformation in rolling of flat product is modeling in ABAQUS and further developed to study the frictional effects on spread and bulge. To predict the magnitude of bulging , the rolling process is approximated by successive forging steps. The elongation or the average spread at each step from the previous calculations are u...

PURPOSE In this study, the authors sought to determine (a) how specific vocal fold structural and vibratory features relate to breathy voice quality and (b) the relation of perceived breathiness to 4 acoustic correlates of breathiness. METHOD A computational, kinematic model of the vocal fold medial surfaces was used to specify features of vocal fold structure and vibration in a manner consis...

light-weight and high strength alloys such as al-mg alloys are used in order to reduce the weight of industrial components. however these materials should be formed at elevated temperatures due to their poor formability at room temperature. hot metal gas forming is one of the high-tech forming processes that is used to solve this problem. recent investigation on tube hydroforming showed positiv...

AIM To explore the efficacy of tear trough deformity treatment with the use of hyaluronic acid gel or autologous fat for soft tissue augmentation and fat repositioning via arcus marginalis release. MATERIAL AND METHODS Seventy-eight patients with the tear trough were divided into three groups. Class I has tear trough without bulging orbital fat or excess of the lower eyelid skin. Class II is ...

Introduction: To investigate how 1% procaine injection therapy, one of the neural therapeutic agents, affects neck disability and pain intensity in patients who have cervical discopathies that are causing chronic and/or functional limitations Methods: The records 58 diagnosed with discopathy were examined. Range Motion values, Neck Disability Questionnaire Visual Analog Scale scores compared at...