We aim to find a link between keratokonus (KC) and bullous keratopathy (BK), and extra cellular matrix re-modellation molecules. The activities of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), pro-matrix metalloproteinase-13 (proMMP-13) and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) were measured using immunoassay in three human corneal tissue layers (epi...

To evaluate the efficacy of amniotic membrane in the management of painful bullous keratopathy secondary to the intractable glaucoma and in preventing exposure of drainage devices, we inserted Ahmed valve with amniotic membrane patch graft over the implant itself, and debrided corneal epithelium with amniotic membrane graft over the exposed stroma as a single operation. During the follow-up per...

PURPOSE To analyze the indications and outcomes of phototherapeutic keratectomy (PTK) in the developing world. METHODS In this retrospective study, the records of 203 consecutive eyes of 191 patients who had undergone PTK at a tertiary eye care center were evaluated. The parameters assessed were indications of PTK, demographic features, best spectacle-corrected visual acuity (BSCVA), and pach...

A 20 year-old man presented with redness, severe visual loss and progressive protrusion of a horn-like mass from the palpebral fissure of his left eye (Fig. 1). He reported gradual appearance of a bubbly tissue on the left cornea progressively growing out of the palpebral fissure over the past several months. He had history of ocular trauma with a piece of glass from an exploding vial with unkn...

AIMS This study was designed to investigate the therapeutic potential of excimer laser for recurrent painful erosions in patients not suited to treatment with penetrating keratoplasty. METHODS Phototherapeutic keratectomy (PTK) with the excimer laser was performed prospectively on a series of 13 eyes of 12 patients with recurrent corneal erosions in connection with bullous keratopathy of vari...

purpose : the aim of this study was to determine indications of keratoplasty during 7 years (1999–2006) in emam-rreza and vali-asr teaching hospitals of birjand university of medical sciences. methods : medical records of all patients who underwent penetrating keratoplasty (pk) in teaching hospitals of birjand university of medical sciences from 1999 to 2006 were investigated retrospectively. t...

purpose: to determine the indications for and surgical techniques of corneal transplantation at labbafinejad medical center (lmc) from 2004 to 2007. methods: in this descriptive study, records of 756 patients who had undergone corneal transplantation from october 2004 to october 2007 were reviewed. results: overall, 504 male (64.9%) and 272 female (35.1%) subjects with mean age of 41.29±21.25 (...

Bullous Keratopathy, a severe edema of the corneal stroma and epithelium with a characteristic bulla formation on the corneal surface, is a rare opthalmological emergency in cats. Rapidly progressive and uncontrollable by medical means, this condition will result in corneal perforation hours after initial presentation if left unattended. Its pathophysiology and treatment options are reviewed in...

Intramembrane changes occurring in dysfunctional corneal endothelial cell membranes were examined using freeze-fracture and transmission electron microscopy techniques. Three categories of dysfunctional endothelium were examined: aphakic bullous keratopathy, pseudophakic bullous keratopathy and Fuchs' endothelial dystrophy. Keratoconus corneas and a donor eye bank eye were examined as normal co...