The title compound, C(7)H(14)N(3) (+)·C(25)H(40)N(3)O(4)Si(2) (-)·CH(3)CN, was obtained by the reaction of 2-nitro-1,3-di(pyridin-2-yl)-1,3-di(tert-butyl-dimethyl-sil-yloxy)propane with 1,3,4,6,7,8-hexa-hydro-2H-pyrimido[1,2-a]pyrimidine. Two hydrogen bonds stabilize the Lewis acid/base pair of the nitro-nate and the guanidinium moiety with N⋯O distances of 2.772 (3) and 2.732 (3) Å. Both hydro...

The crystal structures of a series of 3,39-dinitro-2,29-bipyridine N-oxides and N,N9-dioxides consistently show 1,5 interactions between nitro oxygen atoms and aromatic carbon atoms ((ON)O...C: 2.623(2)–2.839(2) Å) while there are also 1,6 interactions between N-oxide oxygen atoms and nitro nitrogen atoms in most cases (O...N(O2): 2.737(2)–2.874(3) Å). The O...C interactions appears to be a com...

'Ene'-reductases have attracted significant attention for the preparation of chemical intermediates and biologically active products. To date, research has been focussed primarily on Old Yellow Enzyme-like proteins, due to their ease of handling, whereas 2-enoate reductases from clostridia have received much less attention, because of their oxygen sensitivity and a lack of suitable expression s...

Nitrated derivatives of unsaturated fatty acids are endogenously formed under oxidative and nitrative stress condition and are defined as electrophilic fatty acids containing a nitro group to a carbon-carbon double bond. Among the most studied nitro derivatives of unsaturated fatty acids are nitro-oleic acid (OA-NO2) and nitro-linoleic acid (LNO2). These products exhibit novel protective action...

Pyrolysis of iron-phenanthroline complexes supported on carbon leads to highly selective catalysts for the reduction of structurally diverse nitroarenes to anilines in 90-99% yields. Excellent chemoselectivity for the nitro group reduction is demonstrated.

a sensitive and simple method for simultaneous preconcentration of trace heavy metal ions in some cerealand vegetable samples has been reported. the method is based on the adsorption of cu2+, fe3+, zn2+ and pb2+on 2-(2-nitro-phenylazo)-naphthalen-1-ol (npn) loaded on activated carbon (ac). the adsorbed metals onactivated carbon were eluted using 3 ml 4 mol l−1 nitric acid. the influences of the...

Increased production of sinefungin, a very potent antifungal and antiparasitic nucleoside antibiotic was achieved by medium and strain improvement. When soybean-meal, dextrin and yeast extract were added as carbon and nitrogen sources to the fermentation medium, instead of corn steep liquor, soya-oil and glucose; the antibiotic yield increased from 40 micrograms/ml to 126 micrograms/ml with low...

Nitroalkanes can be profitably employed as carbanionic precursors for the assembly of dihydroxy ketone frameworks, suitable for the preparation of spiroketals. The carbon-carbon bond formation is carried out exploiting nitroaldol and Michael reactions, while the nitro to carbonyl conversion (Nef reaction) ensures the correct introduction of the keto group. Several spiroketal systems endowed wit...

Nitroaromatic compounds are relatively rare in nature and have been introduced into the environment mainly by human activities. This important class of industrial chemicals is widely used in the synthesis of many diverse products, including dyes, polymers, pesticides, and explosives. Unfortunately, their extensive use has led to environmental contamination of soil and groundwater. The nitro gro...

Airborne particles may constitute a health risk to man. For example, diesel emissions have been shown to contribute to the incidence of lung cancer and have been classified as probably carcinogenic to humans (IARC monograph, 1988). Short-term tests for genotoxicity has shown not only diesel exhaust, but also particles from different outdoor and indoor sources be genotoxic. These particles inclu...