نتایج جستجو برای: cell cycle
تعداد نتایج: 1862685 فیلتر نتایج به سال:
background: breast cancer is the most common diagnosed cancer among women in the world. snail1 plays a role in the development of the invasive phenotypes of cancer, neural cell differentiation, cell division and apoptosis in tumor cells. traces of snail1 in metastasis of breast cancer to bone are observed. the aim of this study was to investigate the effect of specific snail1 sirnas on the prol...
abstract accumulation of gene changes and chromosomal instability in response to cellular dna damage lead to cancer. dna damage induces cell cycle checkpoints pathways. checkpoints regulate dna replication and cell cycle progression, chromatin restructuring, and apoptosis. checkpoint kinase 2 (chk2) is activated in response to dna lesions. atm phosphorylate chk2. the activated chk2 kinase can p...
مهندسان در طراحی های بزرگ و پیچیده، قبل از ساخت نمونه فیزیکی و برآورد هزینه و زمان ساخت آن احتیاج به شبیه سازی کامپیوتری سخت افزار دارند. از طرفی سرعت شبیه سازهای متداول برای حجم بزرگ مدار بسیار کند می شود و این به دلیل محاسبات زیادی است که برای بدست آوردن اطلاعات ریز زمانی مدار انجام می شود. اما در بسیاری از موارد یک طراح احتیاج به دیدن درستی عملکرد طرح خود دارد و نه اطلاعات ریز زمانی آن. در ا...
Background and Objective: The cell division cycle 25 (CDC25)is a familyof highly conserved dual-specificity phosphatases that activate cyclin-dependent kinase complexes. These complexes are the main cell cycle regulators. Mammalian cells ,exposure to DNA damaging radiations such as ionizing radiation and ultraviolet light, prevent cell cycle progression by activation of checkpoint pathways an...
در این پایان نامه خصوصیات کلی شبیه سازی cycle-based معرفی شده و نحوه انجام شبیه سازی cycle-based در سطح گیت و سطح انتقال ثبات مورد بررسی موشکافانه قرار گرفته است . در این پایان نامه همچنین محدودیتهای شبیه سازی cycle-based معرفی شده و راه حلهایی برای این مشکلات ارائه شده است . به موازات این پایان نامه و برای اثبات صحت نظریه های مطرح شده و راه حلهای ارائه شده در آن، یک شبیه ساز cycle-based برای ز...
Introduction: Prunus armeniaca is one member of the Rosaceae family. Antitumor activity of this family on the colon, prostate, bladder, cervix, lung and breast cancers has been proven in previous research, which is attributed to a natural compound called amygdalin. Therefore, in this study, we investigated the effect of apricot kernel extract on acute leukemia that has not been studied before. ...
introduction: bleomycin sulfate is a dna damaging agent used in cancer chemotherapy. the effect of this drug on various cell cycle stages might be different, thus inducing different modes of death (apoptotic or mitotic death). the aim of this investigation was to study the effects of bleomycin on human peripheral blood lymphocytes at various cell cycle stages by two different end points (induct...
Background and Objective: This study was conducted to evaluate the effect of PectaSol on modification of Doxorubicin (Dox) cytotoxicity and apoptosis and cell cycle in prostate cancer cell lines (DU-145 & LNCaP) Materials and Methods: Human prostate carcinoma DU-145 and LNCaP cell lines were treated with various concentrations of pectaSol,...
background: we had previously identified the genes involved in squamous cell carcinoma of the head and neck using differential display and dna microarray techniques. we also reported the first analytical study on a novel human gene called loc92912, which was identified by differential display as a gene up-regulated in such carcinomas. loc92912, which is a putative member of the e2 ubiquitin con...
exergy analysis of an integrated molten carbonate fuel cell-turbo expander-steam turbine hybrid cycle has been presented in this study. the proposed cycle has been used as a sustainable energy approach to provide a micro hybrid power plant with high exergy efficiency. to generate electricity by the mentioned system, an externally reformed molten carbonate fuel cell located upstream of the combi...
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