Ageing is the main risk factor for major non-communicable chronic lung diseases, including chronic obstructive pulmonary disease, most forms of lung cancer and idiopathic pulmonary fibrosis. While the prevalence of these diseases continually increases with age, their respective incidence peaks at different times during the lifespan, suggesting specific effects of ageing on the onset and/or path...

Background- Chronic Obstructive Pulmonary disease (COPD) as defined by Global Initiative for Lung Disease (GOLD) is a common preventable and treatable disease, characterized persistent airflow limitation that usually progressive associated with an enhanced chronic inflammatory response in the airways lung to noxious particles or gases. Objectives-To evaluate outcome of NIV terms ofTime reversio...

A case of a 19-year-old with severe chronic obstructive pulmonary disease is presented. This case illustrates genetic (severe alpha-1 antitrypsin deficiency) and host factors (such as developmental diaphragmatic hernia and the innate response to injury), and environmental (high oxidative stress and lung injury) interactions that lead to severe chronic obstructive lung disease. The development o...

 Create insight in the epidemiology of obesity in patients with chronic obstructive pulmonary disease;  Understand the impact of obesity on lung function, symptoms and exercise capacity in patients with chronic obstructive pulmonary disease;  Learn about the obesity paradox in patients with chronic obstructive pulmonary disease;  Receiving insight in the importance of nutritional counsellin...

There is now compelling evidence that proteinases and oxidative stress play pathogenetic roles in the following pathologies in chronic obstructive pulmonary disease: airspace enlargement; chronic inflammation in the airways, lung interstitium, and alveolar space; and mucus hypersecretion in the large airways. Proteinases and oxidants may also contribute to remodeling processes in the small airw...

Chronic obstructive pulmonary disease (COPD) is characterized by tissue loss and a growing restriction of airflow. Due to chronic inflammation brought on extended exposure noxious particles or gases, most often cigarette smoke, it linked structural abnormalities in the lungs. Airway constriction reduction lung recoil are results inflammation. In affluent countries, majority COPD cases caused to...

Chronic obstructive pulmonary disease (COPD) and lung cancer are two leading causes of death in the world, which are projected to rank fourth and sixth by 2030 [1], respectively. Both are caused by cigarette smoking and there is an increasing evidence linking the two diseases through epidemiologic and genetic studies The Impact of Chronic Obstructive Pulmonary Disease on Lung Cancer Survival: A...

Beta 2 agonists reduce airway hypersensitivity to bronchoconstrictor stimuli acutely in patients with asthma and chronic obstructive lung disease. To determine whether these drugs also protect against excessive airway narrowing, the effect of inhaled salbutamol on the position and shape of the dose-response curves for histamine or methacholine was investigated in 12 patients with asthma and 11 ...

1. Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. Am J Respir Crit Care Med. 2017;195(5):557-582. doi:10.1164/rccm.201701-0218PP CrossRef Google Scholar