background: the purpose of this study was to describe the association of mthfr gene single nucleotide polymorphisms (c677t and a1298c) and maternal supplementary folate intake with orofacial clefts in the iranian population. methods: in this case-control study, peripheral venous blood was taken from 65 patients with orofacial clefts and 215 unaffected controls for dna extraction and kept in edt...

a 39-year-old pregnant woman at 38 weeks of gestation was referred with labor pain to a hospital. she had consanguinity with her husband. a female newborn had multiple craniofacial anomalies and phocomelia in right upper limb. the disease locus was assigned to chromosome17q21. four days later, infant died of cardiopulmonary arrest.

During sentence processing there is a preference to treat the first noun phrase found as the subject and agent, unless marked the other way. This preference would lead to a conflict in thematic role assignment when the syntactic structure conforms to a non-canonical object-before-subject pattern. Left perisylvian and fronto-parietal brain networks have been found to be engaged by increased comp...

introduction: cleft lip (cl) and cleft palate (cp) are among the most common congenital anomalies. constituting 65% of head and neck anomalies in isolated or syndromic forms, they are considered as the most common head and neck congenital deformities in children. methods: 15 children from the tabriz children hospital were evaluated in this descriptive-analytic cross sectional study that possess...

introduction: cleft lip and palate are among the most common congenital anomalies worldwide. this study was conducted in order to explore the incidence and related factors of cleft lip and/or palate (cl/p) among live births in mashhad, north-eastern iran.   materials and methods: in this cross-sectional study, records of 28,519 infants born between march 1982 and march 2011 at three major hospi...

results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...

Objectives: Cleft Palate (CP) with or without Lip (CL/P) are the most common craniofacial birth defects. and (CLP) can affect children’s communication skills. The present study aimed to evaluate language production skills concerning morphology syntax (morphosyntactic) in children CLP. Methods: In current cross-sectional study, 58 Persian-speaking (28 CLP & 30 anomalies=non-clefts) participa...