PURPOSE To compare findings of normal angles with those from primary congenital glaucoma in order to clarify the pathogenic mechanisms of the disease and to explain the success of surgical treatment in some of these patients. METHODS Adult normal eyes from cadavers and fragments of surgical trabeculectomies from patients with primary congenital glaucoma previously treated with goniotomy were ...

The review is devoted to the genetic nature of congenital glaucoma (CG) and presents clinical forms hereditary single nucleotide polymorphisms identified by genome-wide association studies (GWAS). Glaucoma a genetically heterogeneous disease, patients with same diagnosis often have different molecular causes. role mutations in CYP1B1 gene has been proven pathogenesis hydrophthalmos; MYOC — juve...

This article aims to provide a concise overview of the existing literature on Sturge-Weber syndrome in infants. comprehensive review presents key information regarding prevalence, clinical characteristics, diagnostic methods, and available treatments based recent global research. is rare congenital neurocutaneous disorder, affecting approximately 1 20,000 50,000 new-born, caused by somatic muta...

Congenital iris ectropion is a rare condition; non-progressive anomaly characterised by the presence of iris pigment epithelium on the anterior surface of the iris stroma and is frequently associated with anterior iris insertion, dysgenesis of the drainage angle and glaucoma. This paper describes unusual case of bilateral case of congenital iris ectropion in adult patient with pupillary abnorma...

purpose: to evaluate intermediate-term results of baerveldt tube implantation for treatment of refractory glaucoma in young patients. methods: we retrospectively studied 14 eyes of 11 consecutive patients aged<20 years with refractory glaucoma who underwent baerveldt tube implantation after 1 to 3 previous surgical procedures. the glaucoma was congenital in eight eyes and following congenital c...

The prevalence and mode of inheritance of major genetic eye diseases have been investigated in China since the establishment of the Section of Ophthalmic Genetics of the Chinese Society of Genetics. Mass screening of genetic eye diseases has been undertaken in many districts in China, covering more than 700,000 people, and more than 5000 pedigrees of genetic eye diseases have been collected and...

Canine glaucoma encompasses a diverse group of diseases associated with an increase in intraocular pressure that results in retinal ganglion cell death and eventual blindness. Dogs may have congenital, primary, or secondary glaucoma. The diagnosis is made by recognizing clinical signs, interpreting ophthalmic examination findings, and determining intraocular pressure. Identifying the underlying...