purpose: to report two sisters with congenital myasthenic syndrome (cms) masquerading as myasthenia gravis. patients and findings: two six and seven years old sisters presented with variable strabismus, ptosis, and fatigue. all symptoms were aggravated with exercise and improved with rest. intramuscular prostigmin injection decreased their symptoms. a diagnosis of cms was made according to earl...

an aborted female holstein foetus with marked generalized anasarca was referred to the excellence centre for ruminant abortion and neonatal mortality, ferdowsi university of mashhad. on postmortem examination, red-tinged ascites, pale and firm liver with extreme irregularity and numerous round to oval slightly raised foci on the capsular surface were seen. histological examination revealed wide...

atrial septal defect (asd) is a common congenital anomaly that has low surgical mortality and morbidity. we report a very rare case of a low-lying asd, combined with the drainage of the inferior vena cava and the left superior vena cava into the left atrium. this combination was associated with an unroofed coronary sinus. we also describe an iatrogenic surgical diversion of the inferior vena ca...

background the most common space occupying lesions of the fetal thorax are congenital diaphragmatic hernia (cdh), congenital cystic adenomatoid malformation (ccam), and bronchopulmonary sequestration (bps). although applications of prenatal mri have been vastly improved in the recent years, its use in the assessment of space occupying lesions of the fetal chest differs among centers. objectives...

Congenital methemoglobinemia is a rare cause of cyanosis. We report a case of a girl, 17 years old with peripheral cyanosis and normal cardio-pulmonary system. She was diagnosed as a case of methemoglobinemia based on findings of polycythemia and HbM band on hemoglobin electrophoresis. We emphasize the importance of this rare entity in the differential diagnosis of cyanosis.

the most common congenital diseases in children is congenital heart disease. factors such as environment, genetic, old maternal age during pregnancy, maternal disease and using medicine in pregnancy, prematuritiy, and specific seasons are significant in the prevalence of disease.materials and methods: a cross sectional study was conducted to investigate the status of children with congenital he...

purpose: to determine the prevalence and to describe the demographic pattern of congenital cataract surgery performed at a referral hospital in iran during four consecutive years with respect to sex inequality in receiving eye care. methods: all children aged 15 years or less who had undergone congenital cataract surgery between 2006 and 2009 in labbafinejad medical center were enrolled in this...

background congenital pulmonary lesions may be diagnosed through ultrasonographic screenings or be revealed as causes of respiratory distress in the neonatal period and infancy. less commonly, they are detected as incidental features. objectives our study represents the diversity of congenital pulmonary lesions and their characteristics during an 11-year period in a referral teaching children’s...

Background: Congenital hypothyroidism increases the risk of sensorineural hearing loss (SNHL). Children with hearing impairment are prone to communication disorders. The present study aimed to determine the prevalence of SNHL in patients with congenital hypothyroidism in Qazvin, Iran. Methods: This cross-sectional study was conducted on children with transient or permanent congenital hypothyroi...