Bronchopulmonary injury secondary to smoke inhalation is a significant comorbid factor following major thermal trauma. The present study evaluates the effects of pentoxifylline (PTX) on pulmonary function in an ovine model of inhalation injury. Following smoke exposure to produce a moderate inhalation injury, 16 animals were divided into two groups. Group 1 animals (n = 8) were untreated; Group...

Total, free and conjugated forms (steryl esters, steryl glycosides and acyl steryl glycosides) of sterols from three microalgae that are extensively used in mariculture (Tetraselmis chuii, Nannochloropsis salina and Skeletonema costatum) were examined. The results revealed that cholesterol is the only common fraction detected in all investigated species and distributed in free and all conjugate...

We examined whether oxidized lipids in the diet determine the levels of oxidized lipid in human postprandial serum chylomicrons. After we fed subjects control corn oil containing low quantities of oxidized lipid, the levels of conjugated dienes in the chylomicron fraction were low (9.67 +/- 0.92 nmol/mumol triglyceride), and no thiobarbituric acid-reactive substances (TBARS) could be detected. ...

We have analyzed the results of investigation alterations in indices pro-oxidant (conjugated diene and malondialdehyde) antioxidant (superoxide dismutase, ceruloplasmin, catalase) systems guinea pigs’ lungs experimental allergic alveolitis dynamics EAA development under conditions immobilization stress. The was conducted on 62 female pigs weighing 180-220 g, divided into 4 groups: I – intact (n...

The five-membered zirconacycloallenoids 2 react rapidly with dihydrogen under mild conditions to yield the corresponding (s-cis-conjugated diene)zirconocenes 3. The reaction involves splitting of the H(2) molecule between the metal center and a ligand carbon atom.

Low-density lipoprotein (LDL) oxidation was measured in vitro to determine intraindividual variability and to relate oxidation to linoleic acid enrichment. Intraindividual variability was determined for eight subjects on 3 consecutive days after 14 d on a fixed diet. Coefficients of variation were 7.49 +/- 1.50%, 6.58 +/- 1.16%, and 4.58 +/- 0.77% for oxidation rate, lag time, and diene concent...

 ABSTRACT Background: Dietary antioxidant intake has been reported to be inversely associated with coronary miery disease. To clarify the possible role oflipophilic antioxidants in the prevention of atherosclerosis, we investigated the effects ofubiquinol-1 0 and ~-carotene on the susceptibility oflow-density lipoprotein(LD L) to oxidative modification. Methods: In this study, first "u...