Corneal collagen crosslinking (CXL) is a promising new treatment modality designed to stabilize or decrease the progression of keratoconus, as well as other cornealthinning processes such as ectasia after LASIK or PRK. An increase in corneal biomechanical strength after CXL slows the progression of keratoconus and other forms of ectasia with few reported complications. Underlying the efficacy o...

Corneal thickness measurements find applications in areas such as diagnosis and management of corneal disorders and corneal surgery. We present a technique for the measurement of corneal thickness using a CCD camera mounted on a slit-lamp biomicroscope and common image processing software. Thickness measurements were performed on three RGP contact lenses of known thickness with an average error...

PURPOSE Corneal thinning disorders weaken the mechanical strength of affected corneas, suggesting that photorefractive procedures may be contraindicated in keratoconus. Few cases have been reported to confirm this hypothesis. METHODS A 45-year-old man had two laser in situ keratomileusis (LASIK) procedures and one photorefractive keratectomy (PRK) performed on his left eye, and three LASIK pr...

Over the last two decades, there has been growing interest in assessing corneal biomechanics different diseases, such as keratoconus, glaucoma, and disorders. Given interaction structural continuity between cornea sclera, evaluating may give us further insights into pathogenesis, diagnosis, progression, management of glaucoma. Therefore, some authorities have recommended baseline evaluations al...

PURPOSE Hyaluronan (HA) is a disaccharide polymer capable of binding considerable amounts of water. It is present in trace amounts on the cornea endothelium, and it is not normally found in the epithelium or stroma. A specific histochemical stain was used to test for HA in a wide variety of corneal disorders. METHODS. Eighty-six human corneal tissue specimens were examined histochemically for H...

Proper wound healing is vital for maintenance of corneal integrity and transparency. Corneal epithelial damage is one of the most frequently observed ocular disorders. Because clinical options are limited, further novel treatments are needed to improve clinical outcomes for this type of disease. In the present study, it was found that placental extract-derived dipeptide (JBP485) significantly i...

INTRODUCTION Biomechanical changes in the cornea during pregnancy might lead to pathological conditions such as corneal perforation or melting. CASE PRESENTATION A 33-year-old Asian female who underwent penetrating keratoplasty in both eyes developed corneal melting in the right eye and marginal keratitis in the left eye in her fifth month of pregnancy. Marginal keratitis in the left eye imme...

Concern has arisen in recent years that selection for extreme facial morphology in the domestic dog may be leading to an increased frequency of eye disorders. Corneal ulcers are a common and painful eye problem in domestic dogs that can lead to scarring and/or perforation of the cornea, potentially causing blindness. Exaggerated juvenile-like craniofacial conformations and wide eyes have been s...