Porokeratosis is a rare epidermal disorder characterized by annular or linear hyperkeratotic plaques with slightly raised thread-like borders, and in most cases, atrophic centers. Disseminated superficial porokeratosis and disseminated superficial actinic porokeratosis (DSAP), which primarily involve sun-exposed areas, are common types of porokeratoses. Histologically, a column of parakeratotic...

Porokeratoses are a group of hereditary or acquired disorders characterized by annular lesions with an atrophic center and a prominent peripheral ridge. Pathologically, porokeratosis is characterized by the presence of abnormal clones of keratinocytes that form a column of parakeratotic cells, called the cornoid lamella. Fifteen percent of patients of disseminated superficial actinic porokerato...

We report here a rare case of porokeratosis in which two different clinical types of porokeratosis (linear porokeratosis and disseminated superficial actinic porokeratosis) coexisted. A 7-year-old girl developed a centrifugal lesion on her left abdomen at the age of 2, disseminated superficial actinic porokeratosis on her face at the age of 3 after ultraviolet exposure, and linear porokeratosis...

Porokeratosis is a disorder of keratinisation whose pathogenesis is yet unclear. It has been postulated that it results from the proliferation of an abnormal clone of keratinocytes, triggered by several factors, such as immunosuppression or prolonged ultraviolet exposure. Various clinical forms are recognized whose common denominator is a keratotic ring surrounding a central zone of atrophy. Th...

Disseminated superficial porokeratosis (DSP) is a rare variant of porokeratosis, which is characterized histologically by cornoid lamella and clinically by central atrophy with elevated borders. DSP is usually associated with immunosuppressive states and hematopoietic malignancies, but rarely with malignancies of visceral organs. A 65-year-old male presented with numerous brownish macules with ...

More than a century ago, two Italian dermatologists independently described a new keratotic disorder [1,2] which was called porokeratosis by Mibelli [1]. After these first descriptions, at least four variants of porokeratosis have been recognized. Clinically all these dermatological disorders are characterized by diffuse annular lesions surrounded by a raised, sharply marginated, keratotic bord...

Inflammatory linear verrucous epidermal nevus is a rare variant of nevoid linear inflammatory dermatoses which appear most often in first six months of life and persists for many years or even whole life. Clinically it often shares many features with linear psoriasis, linear porokeratosis and other linear dermatoses which can usually be differentiated by an established set of clinical and histo...

Circumscribed palmar or plantar hypokeratosis (CPH) is a rare condition, usually asymptomatic, consisting of a well-demarcated erythema with central depression and hyperkeratotic border which divides it from the normal skin. We report a 77-year-old woman with a characteristic lesion of circumscribed palmar hypokeratosis on the right palm. Clinically, the lesion simulated porokeratosis of Mibell...

Porokeratosis of Mibelli is a keratinization disorder due to cellular clones that show different degress of dysplasia. Sometimes, these lesions develop on the previously traumatized or burnt skin. Herein, a 24 – year- old female patient is presented with three facial skin lesions on her right cheek on a previous old scar due to cutaneous leishmaniasis is presented. The larger lesion was an eryt...