نتایج جستجو برای: crohn
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In 1932, Crohn, Ginzburg and Oppenheimer published their classical paper on regional ileitis in the Journal of the American Medical Association (JAMA).' Since then, it has been a popular pastime to document the many case descriptions ofCrohn's disease whch were published beforehand.2-4 Most of these were brief reports of small numbers.5-7 The most thorough studies were those of Moschowitz and W...
The incidence of primary Crohn colitis is uncommon and surgical treatment has remained controversial, although most patients with Crohn colitis eventually require surgical intervention. This study aims to compare the operative outcomes of patients who underwent segmental versus either total colectomy or total proctocolectomy for Crohn colitis and to assess potential risk factors associated with...
Background and purpose: Crohn disease (CD) is an autoimmune disorder in which a failure of tolerance to the intestinal antigens plays a pivotal role in the pathogenesis of this disease. Treg cells control immune responses to self and foreign antigens and have an important role in maintaining self-tolerance. In this study we evaluated the frequency of Tregs in the peripheral blood of patients wi...
OBJECTIVE The purpose of this article is to review the technique of performing MR enterography examinations and to review the imaging findings suggestive of Crohn disease. This article will also allow the reader to self-assess and improve his or her skills in the performance and interpretation of MR enterography examinations. CONCLUSION MRI plays a valuable role in providing accurate informat...
A small number of cases of Crohn disease associated with myelodysplastic syndromes or leukemia have been reported in adults in the last 25 years in the English-language medical literature. The authors report a case of a 9-year-old boy who developed Crohn disease and myelodysplastic syndrome concurrently. Analysis of his bone marrow showed a chromosome 20 abnormality. Although chromosome 20 abno...
BACKGROUND Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung disease. CASE PRESENTATION A 6.5-year-old girl is described with early recurrent bronchopulmonary symptoms both at presentation and in the quiescent phase of Crohn disease. Pulmonary function tests (lung volumes and flows, bronchi...
of terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted noncommercial use, distribution, and reproduction in any medium provided article is properly cited. a Department of Pathology and Laboratory Medicine – David Geffen School of Medicine – University of California, Los Angeles/CA – USA. b Department of Pathology and Laboratory Medicine – Weill Cornell Me...
The relationship between the host and its microbiota is challenging to understand because both microbial communities and their environments are highly variable. We have developed a set of techniques based on population dynamics and information theory to address this challenge. These methods identify additional bacterial taxa associated with pediatric Crohn disease and can detect significant cha...
background and aims: in diagnosing inflammatory bowel disease, one of diagnostic way is upper gastrointestinal endoscopy, which helps in differential diagnosis of unspecified colitis as well. the aim of this study was to investigate the necessity of upper gastrointestinal endoscopy in patients with inflammatory bowel disease. materials and methods: in this descriptive cross-sectional study, 3...
Infliximab is one of the most widely used tumour necrosis factor-alpha (TNF) inhibitors for control of Crohn disease. We report the case of a patient with ileocolonic Crohn disease developing major arterial thrombosis after treatment with infliximab. After conservative management and infliximab withdrawal, thrombus dissolution and vessel recannalisation were observed. Few cases of arterial thro...
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